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Hus1b Gene Detail
Summary
  • Symbol
    Hus1b
  • Name
    HUS1 checkpoint clamp component B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2671003
    NCBI Gene: 210554
Location & Maps
more
  • Sequence Map
    Chr13:30946573-30947759 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1187 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 13.33 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    HUS1B, HUS1 checkpoint clamp component B
  • Vertebrate Orthologs
    4
  • Human Ortholog
    HUS1B, HUS1 checkpoint clamp component B
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 135458
    neXtProt AC: NX_Q8NHY5

  • Chr Location
    6p25.3; chr6:655939-656964 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Hus1b
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000675 VEGA Gene Model | MGI Sequence Detail 1187 C57BL/6J ±  kb
transcript OTTMUST00000001303 VEGA | MGI Sequence Detail 1187 Not Applicable  
polypeptide OTTMUSP00000000620 VEGA | MGI Sequence Detail 276 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    17 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:75801 Hang H, et al., Identification and Characterization of a Paralog of Human Cell Cycle Checkpoint Gene HUS1. Genomics. 2002 Apr;79(4):487-92
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory