Trp53i11 MGI Mouse Gene Detail - MGI:2670995 - transformation related protein 53 inducible protein 11

Symbol

Trp53i11
Name

transformation related protein 53 inducible protein 11
Synonyms

Tp53i11

Feature Type

protein coding gene
IDs

MGI:2670995
NCBI Gene: 277414
Alliance

genome feature page
Transcription Start Sites

10 TSS

Sequence Map

Chr2:93017893-93032104 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 2, 51.37 cM
Mapping Data

1 experiment

SNPs within 2kb

383 from dbSNP Build 142
Strain Annotations

19

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2670995	protein coding gene	Chr2:93017694-93032104 (+)
129S1/SvImJ	ENSMUSG00200053615	protein coding gene	Chr2:89935165-89949381 (+)
A/J	ENSMUSG00195053145	protein coding gene	Chr2:90072080-90086289 (+)
AKR/J	ENSMUSG00220050338	protein coding gene	Chr2:89869754-89883952 (+)
BALB/cJ	ENSMUSG00180054753	protein coding gene	Chr2:89969861-89984074 (+)
C3H/HeJ	ENSMUSG00175051595	protein coding gene	Chr2:90234225-90248421 (+)
C57BL/6NJ	ENSMUSG00215053570	protein coding gene	Chr2:90062411-90076624 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023985	protein coding gene	Chr2:87316330-87330508 (+)
CAST/EiJ	ENSTCUG00005050391	protein coding gene	Chr2:89480309-89494500 (+)
CBA/J	ENSMUSG00210029011	protein coding gene	Chr2:90242315-90256526 (+)
DBA/2J	ENSMUSG00185056822	protein coding gene	Chr2:89966186-89980400 (+)
FVB/NJ	ENSMUSG00205051529	protein coding gene	Chr2:89256210-89270415 (+)
JF1/MsJ	ENSUMUG00000030861	protein coding gene	Chr2:89789526-89803340 (+)
LP/J	ENSMUSG00230040628	protein coding gene	Chr2:91716679-91730892 (+)
NOD/ShiLtJ	ENSMUSG00190042868	protein coding gene	Chr2:90044842-90059051 (+)
NZO/HlLtJ	ENSMUSG00225050632	protein coding gene	Chr2:99630717-99644929 (+)
PWK/PhJ	ENSLUMG00010051109	protein coding gene	Chr2:89765100-89779262 (+)
SPRET/EiJ	ENSMSPG00010008860	protein coding gene	Chr2:91738735-91752941 (+)
WSB/EiJ	ENSIUOG00005051688	protein coding gene	Chr2:89771259-89785463 (+)

Human Ortholog

TP53I11, tumor protein p53 inducible protein 11

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TP53I11, tumor protein p53 inducible protein 11
Synonyms

PIG11
Links

HGNC:16842

NCBI Gene ID: 9537

UniProt: O14683
Chr Location

11p11.2; chr11:44885903-44951306 (-) GRCh38

MGI Vertebrate Homology

Trp53i11 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: TP53I11
Gene Tree

Trp53i11

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
15 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Chemically induced (other)

1
Endonuclease-mediated

3
Gene trapped

2
Radiation induced

1
Targeted

3
Genomic Mutations

4 involving Trp53i11
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

26 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

1
GO References

1

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

651
Tissues

21
cDNA Data

7
Literature Summary

6

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN tp53i11a, tp53i11b

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All Sequences

81
RefSeq

38
UniProt

2
CCDS

CCDS16452.1

Ensembl

ENSMUSG00000068735 (Evidence)
NCBI Gene

277414

			Length	Strain/Species	Flank
genomic	ENSMUSG00000068735	Ensembl Gene Model \| MGI Sequence Detail	14212	C57BL/6J	± kb
transcript	ENSMUST00000111266	Ensembl \| MGI Sequence Detail	2703	Not Applicable
polypeptide	ENSMUSP00000106897	Ensembl \| MGI Sequence Detail	189	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000016560 tumor protein p53-inducible protein 11

(term hierarchy)
InterPro Domains

IPR028266 Tumor protein p53-inducible protein 11

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All nucleic 8

cDNA 8

Microarray probesets 3

Summaries

All 39

Developmental Gene Expression 6

Gene Ontology 1

Phenotypes 15
Earliest

J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Trp53i11:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr18978	Chr2:93017144-93017153 (+)	-744 bp
Tssr18979	Chr2:93017887-93017898 (+)	0 bp
Tssr18980	Chr2:93017904-93017915 (+)	17 bp
Tssr18981	Chr2:93017919-93017986 (+)	60 bp
Tssr18982	Chr2:93018117-93018128 (+)	230 bp
Tssr18985	Chr2:93028858-93028903 (+)	10,988 bp
Tssr18986	Chr2:93030152-93030184 (+)	12,275 bp
Tssr18987	Chr2:93030606-93030629 (+)	12,725 bp
Tssr18988	Chr2:93030638-93030652 (+)	12,752 bp
Tssr18989	Chr2:93031922-93031960 (+)	14,048 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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