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BC048403 Gene Detail
Summary
  • Symbol
    BC048403
  • Name
    cDNA sequence BC048403
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670984
    NCBI Gene: 270802
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:121739930-121752865 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 69.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    115 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670984
protein coding gene Chr10:121739930-121752878 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017786
protein coding gene Chr10:125032475-125048014 (+)
A/J MGP_AJ_G0017761
protein coding gene Chr10:120033259-120046994 (+)
AKR/J MGP_AKRJ_G0017724
protein coding gene Chr10:123622014-123634962 (+)
BALB/cJ MGP_BALBcJ_G0017725
protein coding gene Chr10:120461030-120473788 (+)
C3H/HeJ MGP_C3HHeJ_G0017549
protein coding gene Chr10:123827496-123840967 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018180
protein coding gene Chr10:129282809-129295737 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015860
protein coding gene Chr10:114354819-114368436 (+)
CAST/EiJ MGP_CASTEiJ_G0017109
protein coding gene Chr10:124218412-124232554 (+)
CBA/J MGP_CBAJ_G0017518
protein coding gene Chr10:134544209-134557127 (+)
DBA/2J MGP_DBA2J_G0017624
protein coding gene Chr10:119170980-119184562 (+)
FVB/NJ MGP_FVBNJ_G0017619
protein coding gene Chr10:118161639-118175089 (+)
LP/J MGP_LPJ_G0017698
protein coding gene Chr10:125557341-125570315 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017647
protein coding gene Chr10:137072865-137087080 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018220
protein coding gene Chr10:123674148-123687272 (+)
PWK/PhJ MGP_PWKPhJ_G0016894
protein coding gene Chr10:119293696-119307390 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016685
protein coding gene Chr10:122546173-122559054 (+)
WSB/EiJ MGP_WSBEiJ_G0017170
protein coding gene Chr10:123863088-123876798 (+)



Homology
more
  • Human Ortholog
    C12orf66, chromosome 12 open reading frame 66
  • Vertebrate Orthologs
    10
  • Human Ortholog
    C12orf66, chromosome 12 open reading frame 66
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 144577
    neXtProt AC: NX_Q96MD2
    UniProt: Q96MD2

  • Chr Location
    12q14.2; chr12:64186312-64222296 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 270802 NCBI Gene Model | MGI Sequence Detail 12936 C57BL/6J ±  kb
transcript NM_173022 RefSeq | MGI Sequence Detail 3130 C57BL/6  
polypeptide Q6P1I3 UniProt | EBI | MGI Sequence Detail 445 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • PDB
  • InterPro Domains
    IPR018544 KICSTOR complex protein C12orf66-like
    IPR038060 KICSTOR complex protein C12orf66-like, central domain superfamily
Molecular
Reagents
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  • All nucleic 17
    Genomic 2
    cDNA 15

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory