Hk3
Gene Detail

Symbol Name ID

Hk3 hexokinase 3 MGI:2670962

Feature Type

protein coding gene

Genetic Map

Chromosome 13

29.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr13:55005985-55021385 bp, - strand From VEGA annotation of GRCm38   15401 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:55633  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

Protein SuperFamily: hexokinase I
Gene Tree: Hk3

Human homologs

Human Homolog		HK3, hexokinase 3 (white cell)
NCBI Gene ID		3101
neXtProt AC		NX_P52790
Human Synonyms		HKIII, HXK3
Human Chr (Location)		5q35.2; chr5:176307870-176326333 (-)  GRCh37.p10

Gene Ontology (GO) classifications

All GO classifications: (23 annotations)

Process	carbohydrate metabolic process, carbohydrate phosphorylation, ...
Component	cytosol, mitochondrion, ...
Function	ATP binding, catalytic activity, ...

External Resources: FuncBase

Expression

Literature Summary: (2 records)
Data Summary: Results (122)    Tissues (98)    Images (5)
Theiler Stages: 22

Assay Type	Results
RNA in situ	122

cDNA source data(20)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(21) cDNA(20) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000032679 (Evidence)
Ensembl Gene Model	ENSMUSG00000025877 (Evidence)
Entrez Gene	212032 (Evidence)
NIA Mouse Gene Index	U034806
EC	2.7.1.1
Consensus CDS Project	CCDS26538.1, CCDS56883.1, CCDS56884.1
International Mouse Knockout Project Status	Hk3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032679	VEGA Gene Model | MGI Sequence Detail	15401	C57BL/6J
transcript	OTTMUST00000081308	VEGA | MGI Sequence Detail	3219	Not Applicable
polypeptide	OTTMUSP00000043473	VEGA | MGI Sequence Detail	922	Not Applicable

All sequences(78) RefSeq(8) UniProt(12)

Polymorphisms

SNPs(125 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001312	Hexokinase
InterPro	IPR019807	Hexokinase, conserved site
InterPro	IPR022673	Hexokinase, C-terminal
InterPro	IPR022672	Hexokinase, N-terminal
Protein Ontology	PR:000008610	hexokinase-3

References

(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:168606 Leite TC, et al., Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice. FEBS Lett. 2011 Jan 3;585(1):92-8
All references(26)