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Hk3
Gene Detail
Symbol

Name
ID
Hk3
hexokinase 3
MGI:2670962
Feature Type
protein coding gene
Genetic Map
Chromosome 13
29.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:55005985-55021385 bp, - strand
From VEGA annotation of GRCm38

  15401 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55633  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken

Protein SuperFamily: hexokinase I
Gene Tree: Hk3

Human
homologs
Human Homolog HK3, hexokinase 3 (white cell)
NCBI Gene ID 3101
neXtProt AC  NX_P52790
Human Synonyms  HKIII, HXK3
Human Chr (Location)  5q35.2; chr5:176880869-176899332 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Genomic Mutations involving Hk3 (1)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Hk3 interacts with 237 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (26 annotations)
Process carbohydrate metabolic process, carbohydrate phosphorylation, ...
Component cytosol, mitochondrion, ...
Function ATP binding, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (122)    Tissues (98)    Images (5)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 122
cDNA source data(20)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(20) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000032679 (Evidence)
Ensembl Gene ModelENSMUSG00000025877 (Evidence)
Entrez Gene212032 (Evidence)
NIA Mouse Gene IndexU034806
EC2.7.1.1
Consensus CDS ProjectCCDS26538.1, CCDS56883.1, CCDS56884.1
International Mouse Knockout Project StatusHk3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032679 VEGA Gene Model | MGI Sequence Detail 15401 C57BL/6J ±  kb
transcript OTTMUST00000081308 VEGA | MGI Sequence Detail 3219 Not Applicable 
polypeptide OTTMUSP00000043473 VEGA | MGI Sequence Detail 922 Not Applicable 

For the selected sequences
All sequences(91) RefSeq(10) UniProt(23)
Polymorphisms
SNPs within 2kb(146 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001312 Hexokinase
InterPro IPR019807 Hexokinase, conserved site
InterPro IPR022673 Hexokinase, C-terminal
InterPro IPR022672 Hexokinase, N-terminal
Protein Ontology PR:000008610 hexokinase-3
References
(Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:168606 Leite TC, et al., Lactate downregulates the glycolytic enzymes hexokinase and phosphofructokinase in diverse tissues from mice. FEBS Lett. 2011 Jan 3;585(1):92-8
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory