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Hk3 Gene Detail
Summary
  • Symbol
    Hk3
  • Name
    hexokinase 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670962
    NCBI Gene: 212032
  • Gene Overview
    MyGene.info: HK3
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55005985-55021385 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 29.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    146 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670962
protein coding gene Chr13:55005985-55021476 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020583
protein coding gene Chr13:54440621-54455964 (-)
A/J MGP_AJ_G0020537
protein coding gene Chr13:52434340-52449773 (-)
AKR/J MGP_AKRJ_G0020515
protein coding gene Chr13:53979358-53994708 (-)
BALB/cJ MGP_BALBcJ_G0020533
protein coding gene Chr13:52675142-52690502 (-)
C3H/HeJ MGP_C3HHeJ_G0020332
protein coding gene Chr13:53801536-53816916 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020967
protein coding gene Chr13:56091505-56122516 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018549
protein coding gene Chr13:50420646-50436101 (-)
CAST/EiJ MGP_CASTEiJ_G0019846
protein coding gene Chr13:53892939-53908604 (-)
CBA/J MGP_CBAJ_G0020292
protein coding gene Chr13:58234160-58249727 (-)
DBA/2J MGP_DBA2J_G0020415
protein coding gene Chr13:52001273-52016629 (-)
FVB/NJ MGP_FVBNJ_G0020394
protein coding gene Chr13:51465750-51481097 (-)
LP/J MGP_LPJ_G0020491
protein coding gene Chr13:54715986-54731319 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020423
protein coding gene Chr13:57736958-57752305 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021010
protein coding gene Chr13:53569285-53584628 (-)
PWK/PhJ MGP_PWKPhJ_G0019602
protein coding gene Chr13:51994138-52009989 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019429
protein coding gene Chr13:52498987-52514423 (-)
WSB/EiJ MGP_WSBEiJ_G0019908
protein coding gene Chr13:53913051-53928400 (-)



Homology
more
  • Human Ortholog
    HK3, hexokinase 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    HK3, hexokinase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HKIII, HXK3
  • Links
    NCBI Gene ID: 3101
    neXtProt AC: NX_P52790
    UniProt: P52790

  • Chr Location
    5q35.2; chr5:176880869-176899373 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025877 Ensembl Gene Model | MGI Sequence Detail 15401 C57BL/6J ±  kb
transcript ENSMUST00000052949 Ensembl | MGI Sequence Detail 3219 Not Applicable  
polypeptide ENSMUSP00000051215 Ensembl | MGI Sequence Detail 922 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 21
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:240028 Bulusu V, et al., Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development. Dev Cell. 2017 Feb 27;40(4):331-341.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory