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Cnksr1 Gene Detail
Summary
  • Symbol
    Cnksr1
  • Name
    connector enhancer of kinase suppressor of Ras 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670958
    NCBI Gene: 194231
  • Gene Overview
    MyGene.info: CNKSR1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:134228041-134238399 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 66.50 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2670958
protein coding gene Chr4:134228041-134238420 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028917
protein coding gene Chr4:136565304-136575632 (-)
A/J MGP_AJ_G0028876
protein coding gene Chr4:130820101-130830464 (-)
AKR/J MGP_AKRJ_G0028828
protein coding gene Chr4:134570315-134580668 (-)
BALB/cJ MGP_BALBcJ_G0028899
protein coding gene Chr4:131465334-131475648 (-)
C3H/HeJ MGP_C3HHeJ_G0028613
protein coding gene Chr4:134812719-134823094 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029341
protein coding gene Chr4:141498602-141508971 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026612
protein coding gene Chr4:123878427-123888959 (-)
CAST/EiJ MGP_CASTEiJ_G0028046
protein coding gene Chr4:132936326-132946735 (-)
CBA/J MGP_CBAJ_G0028578
protein coding gene Chr4:145203895-145214590 (-)
DBA/2J MGP_DBA2J_G0028727
protein coding gene Chr4:131249232-131259546 (-)
FVB/NJ MGP_FVBNJ_G0028695
protein coding gene Chr4:130140435-130150811 (-)
LP/J MGP_LPJ_G0028827
protein coding gene Chr4:136658531-136668859 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028720
protein coding gene Chr4:149711079-149721393 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029379
protein coding gene Chr4:134989283-134999672 (-)
PWK/PhJ MGP_PWKPhJ_G0027766
protein coding gene Chr4:127975310-127985713 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027592
protein coding gene Chr4:130831823-130843410 (-)
WSB/EiJ MGP_WSBEiJ_G0028124
protein coding gene Chr4:135174032-135184346 (-)



Homology
more
  • Human Ortholog
    CNKSR1, connector enhancer of kinase suppressor of Ras 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CNKSR1, connector enhancer of kinase suppressor of Ras 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CNK, CNK1
  • Links
    NCBI Gene ID: 10256
    neXtProt AC: NX_Q969H4
    UniProt: Q969H4

  • Chr Location
    1p36.11; chr1:26177490-26189884 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4604
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CNKSR1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028841 Ensembl Gene Model | MGI Sequence Detail 10359 C57BL/6J ±  kb
transcript ENSMUST00000030645 Ensembl | MGI Sequence Detail 2468 Not Applicable  
polypeptide ENSMUSP00000030645 Ensembl | MGI Sequence Detail 700 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory