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Med13l Gene Detail
Summary
  • Symbol
    Med13l
  • Name
    mediator complex subunit 13-like
  • Synonyms
    2210413I17Rik, 6330591G05Rik, 9030618F05Rik, mKIAA1025, Thrap2, Trap240L
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670178
    NCBI Gene: 76199
Location & Maps
more
  • Sequence Map
    Chr5:118560679-118765438 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      204760 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MED13L, mediator complex subunit 13 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MED13L, mediator complex subunit 13 like
    Orthology source: HGNC, HomoloGene
  • Synonyms
    MRFACD, PROSIT240, THRAP2, TRAP240L
  • Links
    NCBI Gene ID: 23389
    neXtProt AC: NX_Q71F56

  • Chr Location
    12q24.21; chr12:115955771-116277203 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human MED13L associations

Human Disease Mouse Models
       Transposition of the Great Arteries, Dextro-Looped 1; DTGA1   OMIM: 608808
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    45
  • Chemically induced (other)
    1
  • Gene trapped
    41
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Med13l
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056228 VEGA Gene Model | MGI Sequence Detail 204760 C57BL/6J ±  kb
transcript OTTMUST00000138970 VEGA | MGI Sequence Detail 7781 Not Applicable  
polypeptide OTTMUSP00000072979 VEGA | MGI Sequence Detail 2216 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1078 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000010285 mediator of RNA polymerase II transcription subunit 13-like
  • InterPro Domains
    IPR009401 Mediator complex, subunit Med13
    IPR021643 Mediator complex, subunit Med13, N-terminal, metazoa/fungi
Molecular
Reagents
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  • All nucleic 139
    Genomic 1
    cDNA 138

    Microarray probesets 5
Other
Accession IDs
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MGI:1918805, MGI:1922081, MGI:1923449
References
more
  • Summaries
    All 42
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory