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Med13l
Gene Detail
 Symbol
Name
ID
Med13l
mediator complex subunit 13-like
MGI:2670178
Synonyms 2210413I17Rik, 6330591G05Rik, 9030618F05Rik, mKIAA1025, Thrap2, Trap240L
Feature Type protein coding gene
Genetic Map
Chromosome 5
59.10 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:118560719-118765435 bp, + strand
From Ensembl annotation of GRCm38

  204717 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:25256  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Gene Tree: Med13l

Human
homologs
Human Homolog MED13L, mediator complex subunit 13-like
NCBI Gene ID 23389
neXtProt AC  NX_Q71F56
Human Synonyms  PROSIT240, THRAP2, TRAP240L
Human Chr (Location)  12q24.21; chr12:115958576-116277186 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human MED13L
Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(41) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Med13l interacts with 430 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process regulation of transcription, DNA-templated, regulation of transcription from RNA polymerase II promoter, ...
Component mediator complex, nucleus
Function RNA polymerase II transcription cofactor activity
External Resources: FuncBase
Expression
cDNA source data(138)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(139) Genomic(1) cDNA(138)
Microarray probesets(5)
Other database
links
Ensembl Gene ModelENSMUSG00000018076 (Evidence)
Entrez Gene76199 (Evidence)
UniGene206238
DFCITC1579297, TC1588282, TC1602490, TC1604311, TC1666856, TC1674094
DoTSDT.101225314, DT.101736886, DT.40171919, DT.532259, DT.99851399
NIA Mouse Gene IndexU057040, U273291
Consensus CDS ProjectCCDS57375.1
International Mouse Knockout Project StatusMed13l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000018076 Ensembl Gene Model | MGI Sequence Detail 204717 C57BL/6J ±  kb
transcript ENSMUST00000100816 Ensembl | MGI Sequence Detail 9293 Not Applicable 
polypeptide ENSMUSP00000098379 Ensembl | MGI Sequence Detail 2207 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(6) UniProt(5)
Polymorphisms SNPs within 2kb(1099 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1101)
Protein-related
information
ResourceIDDescription
InterPro IPR009401 Mediator complex, subunit Med13
InterPro IPR021643 Mediator complex, subunit Med13, N-terminal, metazoa/fungi
Protein Ontology PR:000010285 mediator of RNA polymerase II transcription subunit 13-like
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(45)
Other
accession IDs
MGI:1918805, MGI:1922081, MGI:1923449

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory