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Med13l Gene Detail
Summary
  • Symbol
    Med13l
  • Name
    mediator complex subunit 13-like
  • Synonyms
    2210413I17Rik, 6330591G05Rik, 9030618F05Rik, mKIAA1025, Thrap2, Trap240L
  • Feature Type
    protein coding gene
  • IDs
    MGI:2670178
    NCBI Gene: 76199
Location & Maps
more
  • Sequence Map
    Chr5:118560679-118765438 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      204760 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 59.10 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    MED13L, mediator complex subunit 13 like
  • Vertebrate Orthologs
    9
  • Human Ortholog
    MED13L, mediator complex subunit 13 like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MRFACD, PROSIT240, THRAP2, TRAP240L
  • Links
    NCBI Gene ID: 23389
    neXtProt AC: NX_Q71F56
    UniProt: Q71F56

  • Chr Location
    12q24.21; chr12:115958576-116277219 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human MED13L associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000056228 VEGA Gene Model | MGI Sequence Detail 204760 C57BL/6J ±  kb
transcript OTTMUST00000138970 VEGA | MGI Sequence Detail 7781 Not Applicable  
polypeptide OTTMUSP00000072979 VEGA | MGI Sequence Detail 2216 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1078 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000010285 mediator of RNA polymerase II transcription subunit 13-like
  • InterPro Domains
    IPR009401 Mediator complex, subunit Med13
    IPR021643 Mediator complex, subunit Med13, N-terminal, metazoa/fungi
Molecular
Reagents
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  • All nucleic 139
    Genomic 1
    cDNA 138

    Microarray probesets 5
Other
Accession IDs
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MGI:1918805, MGI:1922081, MGI:1923449
References
more
  • Summaries
    All 48
    Gene Ontology 4
    Phenotypes 14
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:239012 Aranda-Orgilles B, et al., MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell Stem Cell. 2016 Dec 01;19(6):784-799

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory