Rtn4rl2
Gene Detail

Symbol Name ID

Rtn4rl2 reticulon 4 receptor-like 2 MGI:2669796

Synonyms

Ngr2, Ngrh1, Ngrl3

Feature Type

protein coding gene

Genetic Map

Chromosome 2

49.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr2:84871924-84886710 bp, - strand From VEGA annotation of GRCm38   14787 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:18683  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 cattle; 1 chicken; 2 zebrafish

Gene Tree: Rtn4rl2

Human homologs

Human Homolog		RTN4RL2, reticulon 4 receptor-like 2
NCBI Gene ID		349667
neXtProt AC		NX_Q86UN3
Human Synonyms		NgR2, NGRH1
Human Chr (Location)		11q12.1; chr11:57228339-57244384 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(7) : Targeted(7)
 

Mice homozygous for disruptions in this gene display a normal phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	axon regeneration
Component	anchored to membrane, anchored to plasma membrane, ...
Function	receptor activity

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (158)    Tissues (74)    Images (22)
Theiler Stages: 21, 23, 28

Assay Type	Results
RNA in situ	150
RT-PCR	8

cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(8) cDNA(5) Primer pair(3)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000013729 (Evidence)
Ensembl Gene Model	ENSMUSG00000050896 (Evidence)
Entrez Gene	269295 (Evidence)
DFCI	TC1604776
DoTS	DT.97403975
NIA Mouse Gene Index	U073841
Consensus CDS Project	CCDS16197.1
International Mouse Knockout Project Status	Rtn4rl2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000013729	VEGA Gene Model | MGI Sequence Detail	14787	C57BL/6J
transcript	OTTMUST00000032896	VEGA | MGI Sequence Detail	1303	Not Applicable
polypeptide	OTTMUSP00000014701	VEGA | MGI Sequence Detail	426	Not Applicable

All sequences(23) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(43 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000483	Cysteine-rich flanking region, C-terminal
InterPro	IPR000372	Leucine-rich repeat-containing N-terminal
InterPro	IPR003591	Leucine-rich repeat, typical subtype
Protein Ontology	PR:000014352	reticulon-4 receptor-like 2

References

(Earliest) J:83107 Pignot V, et al., Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor. J Neurochem. 2003 May;85(3):717-28
(Latest) J:191258 Dickendesher TL, et al., NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci. 2012 May;15(5):703-12
All references(32)