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Rtn4rl2
Gene Detail
 Symbol
Name
ID
Rtn4rl2
reticulon 4 receptor-like 2
MGI:2669796
Synonyms Ngr2, Ngrh1, Ngrl3
Feature Type protein coding gene
Genetic Map
Chromosome 2
49.45 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr2:84871924-84886710 bp, - strand
From VEGA annotation of GRCm38

  14787 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18683  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 chicken; 2 zebrafish

Gene Tree: Rtn4rl2

Human
homologs
Human Homolog RTN4RL2, reticulon 4 receptor-like 2
NCBI Gene ID 349667
neXtProt AC  NX_Q86UN3
Human Synonyms  NgR2, NGRH1
Human Chr (Location)  11q12.1; chr11:57460537-57477539 (+)  GRCh38
Alleles
and
phenotypes
All alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a normal phenotype.
 
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process axon regeneration
Component anchored component of membrane, anchored component of plasma membrane, ...
Function receptor activity
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (158)    Tissues (74)    Images (22)
Theiler Stages: 21, 23, 28
Assay TypeResults
RNA in situ 150
RT-PCR 8
cDNA source data(5)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(5) Primer pair(3)
Microarray probesets(1)
Other database
links
VEGA Gene ModelOTTMUSG00000013729 (Evidence)
Ensembl Gene ModelENSMUSG00000050896 (Evidence)
Entrez Gene269295 (Evidence)
DFCITC1604776
DoTSDT.97403975
NIA Mouse Gene IndexU073841
Consensus CDS ProjectCCDS16197.1
International Mouse Knockout Project StatusRtn4rl2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000013729 VEGA Gene Model | MGI Sequence Detail 14787 C57BL/6J ±  kb
transcript OTTMUST00000032896 VEGA | MGI Sequence Detail 1303 Not Applicable 
polypeptide OTTMUSP00000014701 VEGA | MGI Sequence Detail 426 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(12) UniProt(2)
Polymorphisms SNPs within 2kb(49 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
InterPro IPR001611 Leucine-rich repeat
InterPro IPR000372 Leucine-rich repeat-containing N-terminal
InterPro IPR003591 Leucine-rich repeat, typical subtype
Protein Ontology PR:000014352 reticulon-4 receptor-like 2
References (Earliest) J:83107 Pignot V, et al., Characterization of two novel proteins, NgRH1 and NgRH2, structurally and biochemically homologous to the Nogo-66 receptor. J Neurochem. 2003 May;85(3):717-28
(Latest) J:191258 Dickendesher TL, et al., NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci. 2012 May;15(5):703-12
All references(32)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory