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Sytl5 Gene Detail
Summary
  • Symbol
    Sytl5
  • Name
    synaptotagmin-like 5
  • Synonyms
    ENSMUSG00000054453
  • Feature Type
    protein coding gene
  • IDs
    MGI:2668451
    NCBI Gene: 236643
  • Alliance
Location &
Maps
more
  • Sequence Map
    ChrX:9885622-9994543 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 4.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    748 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2668451
protein coding gene ChrX:9747622-9998864 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035560
protein coding gene ChrX:4625870-4733543 (+)
A/J MGP_AJ_G0035537
protein coding gene ChrX:4741182-4839002 (+)
AKR/J MGP_AKRJ_G0035469
protein coding gene ChrX:4783406-4900034 (+)
BALB/cJ MGP_BALBcJ_G0035530
protein coding gene ChrX:4653308-4753499 (+)
C3H/HeJ MGP_C3HHeJ_G0035247
protein coding gene ChrX:4752914-4855509 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036060
protein coding gene ChrX:4702056-4806464 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032929
protein coding gene ChrX:3856328-3941015 (+)
CAST/EiJ MGP_CASTEiJ_G0034539
protein coding gene ChrX:4444352-4548630 (+)
CBA/J MGP_CBAJ_G0035216
protein coding gene ChrX:5077580-5191735 (+)
DBA/2J MGP_DBA2J_G0035369
protein coding gene ChrX:4646902-4738587 (+)
FVB/NJ MGP_FVBNJ_G0035316
protein coding gene ChrX:4479515-4589410 (+)
LP/J MGP_LPJ_G0035451
protein coding gene ChrX:4817528-4922556 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035359
protein coding gene ChrX:4945388-5073358 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036072
protein coding gene ChrX:4554312-4658531 (+)
PWK/PhJ MGP_PWKPhJ_G0034240
protein coding gene ChrX:4163144-4256143 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034081
protein coding gene ChrX:4629266-4720690 (+)
WSB/EiJ MGP_WSBEiJ_G0034675
protein coding gene ChrX:4635939-4738893 (+)



Homology
more
  • Human Ortholog
    SYTL5, synaptotagmin like 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    SYTL5, synaptotagmin like 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    slp5
  • Links
    NCBI Gene ID: 94122
    neXtProt AC: NX_Q8TDW5
    UniProt: Q8TDW5

  • Chr Location
    Xp11.4; chrX:37888915-38128820 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 16345
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: SYTL5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054453 Ensembl Gene Model | MGI Sequence Detail 108922 C57BL/6J ±  kb
transcript ENSMUST00000067529 Ensembl | MGI Sequence Detail 2301 Not Applicable  
polypeptide ENSMUSP00000064826 Ensembl | MGI Sequence Detail 753 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:3710612
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:169802 Kuroda TS, et al., Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains. Biochem Biophys Res Commun. 2002 May 10;293(3):899-906
  • Latest
    J:271120 Scavuzzo MA, et al., Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Rep. 2018 Dec 26;25(13):3811-3827.e7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory