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Gpr142 Gene Detail
Summary
  • Symbol
    Gpr142
  • Name
    G protein-coupled receptor 142
  • Feature Type
    protein coding gene
  • IDs
    MGI:2668437
    NCBI Gene: 217302
  • Gene Overview
    MyGene.info: GPR142
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr11:114798924-114806745 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 80.54 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2668437
protein coding gene Chr11:114797716-114806808 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019361
protein coding gene Chr11:118738871-118747996 (+)
A/J MGP_AJ_G0019330
protein coding gene Chr11:113577002-113584814 (+)
AKR/J MGP_AKRJ_G0019298
protein coding gene Chr11:116936370-116944178 (+)
BALB/cJ MGP_BALBcJ_G0019303
protein coding gene Chr11:113996284-114004663 (+)
C3H/HeJ MGP_C3HHeJ_G0019112
protein coding gene Chr11:117285593-117295294 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019754
protein coding gene Chr11:122303817-122311638 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017377
protein coding gene Chr11:110643602-110651378 (+)
CAST/EiJ MGP_CASTEiJ_G0018666
protein coding gene Chr11:118617126-118624948 (+)
CBA/J MGP_CBAJ_G0019082
protein coding gene Chr11:127191728-127203179 (+)
DBA/2J MGP_DBA2J_G0019194
protein coding gene Chr11:113019367-113026945 (+)
FVB/NJ MGP_FVBNJ_G0019185
protein coding gene Chr11:112502401-112509575 (+)
LP/J MGP_LPJ_G0019264
protein coding gene Chr11:119144285-119155399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019216
protein coding gene Chr11:126351612-126359485 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019791
protein coding gene Chr11:117612490-117620897 (+)
PWK/PhJ MGP_PWKPhJ_G0018431
protein coding gene Chr11:114255407-114263357 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018223
protein coding gene Chr11:117417786-117425405 (+)
WSB/EiJ MGP_WSBEiJ_G0018718
protein coding gene Chr11:117569890-117580259 (+)



Homology
more
  • Human Ortholog
    GPR142, G protein-coupled receptor 142
  • Vertebrate Orthologs
    9
  • Human Ortholog
    GPR142, G protein-coupled receptor 142
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GPRg1b, PGR2
  • Links
    NCBI Gene ID: 350383
    neXtProt AC: NX_Q7Z601
    UniProt: Q7Z601

  • Chr Location
    17q25.1; chr17:74367197-74373008 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034677 Ensembl Gene Model | MGI Sequence Detail 7822 C57BL/6J ±  kb
transcript ENSMUST00000106584 Ensembl | MGI Sequence Detail 1116 Not Applicable  
polypeptide ENSMUSP00000102194 Ensembl | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
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  • All nucleic 7
    Genomic 2
    cDNA 2
    Primer pair 1
    Other 2

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:106981 Susens U, et al., Characterisation and differential expression of two very closely related G-protein-coupled receptors, GPR139 and GPR142, in mouse tissue and during mouse development. Neuropharmacology. 2006 Mar;50(4):512-20
  • Latest
    J:249154 Lin HV, et al., GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism. PLoS One. 2016;11(6):e0157298

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory