Klhl25
Gene Detail

Symbol Name ID

Klhl25 kelch-like 25 MGI:2668031

Synonyms

2810402K13Rik

Feature Type

protein coding gene

Genetic Map

Chromosome 7

43.81 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr7:75848338-75874130 bp, + strand From NCBI annotation of GRCm38   25793 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32546  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: kelch-like protein, gigaxonin type
Gene Tree: Klhl25

Human homologs

Human Homolog		KLHL25, kelch-like family member 25
NCBI Gene ID		64410
neXtProt AC		NX_Q9H0H3
Human Synonyms		ENC2, ENC-2
Human Chr (Location)		15q25.3; chr15:86302557-86338189 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(1) Gene trapped(3)

Gene Ontology (GO) classifications

All GO classifications: (3 annotations)

Process	biological_process
Component	cytoplasm
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (9)    Tissues (5)   
Theiler Stages: 24, 26, 28

Assay Type	Results
RNA in situ	9

cDNA source data(47)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(48) cDNA(48)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000055652 (Evidence)
Entrez Gene	207952 (Evidence)
UniGene	206223
DFCI	TC1578827, TC1582684, TC1616002, TC1620165, TC1691923
DoTS	DT.101389852, DT.110979288, DT.488632
NIA Mouse Gene Index	U008240
Consensus CDS Project	CCDS21369.1
International Mouse Knockout Project Status	Klhl25

Sequences

Length	Strain/Species
genomic	207952	NCBI Gene Model | MGI Sequence Detail	25793	C57BL/6J
transcript	NM_029652	RefSeq | MGI Sequence Detail	3385	C57BL/6
polypeptide	Q8R2P1	UniProt | EBI | MGI Sequence Detail	589	Not Applicable

All sequences(43) RefSeq(6) UniProt(2)

Polymorphisms

SNPs(96 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011705	BTB/Kelch-associated
InterPro	IPR013069	BTB/POZ
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR017096	Kelch-like protein, gigaxonin
InterPro	IPR006652	Kelch repeat type 1
InterPro	IPR015915	Kelch-type beta propeller
Protein Ontology	PR:000009387	ectoderm-neural cortex protein 2

Graphical View of Protein Domain Structure

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(30)

Other accession IDs

MGI:1923803