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Ehbp1 Gene Detail
Summary
  • Symbol
    Ehbp1
  • Name
    EH domain binding protein 1
  • Synonyms
    Flj21950, KIAA0903-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:2667252
    NCBI Gene: 216565
Location & Maps
more
  • Sequence Map
    Chr11:22005828-22342292 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      336465 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 14.10 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    EHBP1, EH domain binding protein 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    EHBP1, EH domain binding protein 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HPC12, NACSIN
  • Links
    NCBI Gene ID: 23301
    neXtProt AC: NX_Q8NDI1

  • Chr Location
    2p15; chr2:62673851-63046487 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 22880
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: EHBP1
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human EHBP1 associations

Human Disease Mouse Models
       Prostate Cancer, Hereditary, 12; HPC12   OMIM: 611868
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Gene trapped
    6
  • Targeted
    4
  • Genomic Mutations
    1 involving Ehbp1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005255 VEGA Gene Model | MGI Sequence Detail 336465 C57BL/6J ±  kb
transcript OTTMUST00000011720 VEGA | MGI Sequence Detail 4821 Not Applicable  
polypeptide OTTMUSP00000005431 VEGA | MGI Sequence Detail 1206 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    1382 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000006941 EH domain-binding protein 1
  • InterPro Domains
    IPR001715 Calponin homology domain
    IPR022735 Domain of unknown function DUF3585
    IPR019448 EEIG1/EHBP1 N-terminal domain
    IPR029944 EH domain-binding protein 1
Molecular
Reagents
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  • All nucleic 7
    cDNA 6
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory