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Irgq Gene Detail
Summary
  • Symbol
    Irgq
  • Name
    immunity-related GTPase family, Q
  • Synonyms
    FKSG27
  • Feature Type
    protein coding gene
  • IDs
    MGI:2667176
    NCBI Gene: 210146
Location & Maps
more
  • Sequence Map
    Chr7:24530689-24538600 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      7912 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 11.32 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    IRGQ, immunity related GTPase Q
  • Vertebrate Orthologs
    7
  • Human Ortholog
    IRGQ, immunity related GTPase Q
    Orthology source: HGNC, HomoloGene
  • Synonyms
    FKSG27, IRGQ1
  • Links
    NCBI Gene ID: 126298
    neXtProt AC: NX_Q8WZA9

  • Chr Location
    19q13.31; chr19:43584367-43596229 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
  • Incidental Mutations
    APF , CvDC
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000058219 VEGA Gene Model | MGI Sequence Detail 7912 C57BL/6J ±  kb
transcript OTTMUST00000142990 VEGA | MGI Sequence Detail 6083 Not Applicable  
polypeptide OTTMUSP00000074568 VEGA | MGI Sequence Detail 583 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    43 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000029561 immunity-related GTPase family Q protein
  • InterPro Domains
    IPR030385 IRG-type guanine nucleotide-binding (G) domain
Molecular
Reagents
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  • All nucleic 103
    cDNA 103

    Microarray probesets 6
References
more
  • Summaries
    All 25
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory