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Tnn Gene Detail
Summary
  • Symbol
    Tnn
  • Name
    tenascin N
  • Synonyms
    tenascin-W, Tnw
  • Feature Type
    protein coding gene
  • IDs
    MGI:2665790
    NCBI Gene: 329278
Location & Maps
more
  • Sequence Map
    Chr1:160085029-160153580 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      68552 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 69.40 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    TNN, tenascin N
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TNN, tenascin N
    Orthology source: HomoloGene
  • Synonyms
    TN-W
  • Links
    NCBI Gene ID: 63923
    neXtProt AC: NX_Q9UQP3

  • Chr Location
    1q23-q24; chr1:175067858-175148066 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 18634
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog
  • HCOP
    human homology predictions: TNN
  • Gene Tree
    Tnn
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    2
  • Targeted
    2
  • Genomic Mutations
    2 involving Tnn
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025412 VEGA Gene Model | MGI Sequence Detail 68552 C57BL/6J ±  kb
transcript OTTMUST00000062571 VEGA | MGI Sequence Detail 5817 Not Applicable  
polypeptide OTTMUSP00000030864 VEGA | MGI Sequence Detail 1560 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    796 from dbSNP Build 142
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000016501 tenascin-N
  • InterPro Domains
    IPR013032 EGF-like, conserved site
    IPR000742 EGF-like domain
    IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
    IPR014716 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
    IPR014715 Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
    IPR020837 Fibrinogen, conserved site
    IPR003961 Fibronectin type III
    IPR013783 Immunoglobulin-like fold
    IPR033080 Tenascin-W
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:83982 Neidhardt J, et al., Tenascin-N: characterization of a novel member of the tenascin family that mediates neurite repulsion from hippocampal explants. Mol Cell Neurosci. 2003 Jun;23(2):193-209
  • Latest
    J:211537 Tucker RP, et al., Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration. J Cell Sci. 2013 Nov 15;126(Pt 22):5111-5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory