Prss42
Gene Detail

Symbol Name ID

Prss42 protease, serine, 42 MGI:2665280

Synonyms

Tessp2

Feature Type

protein coding gene

Genetic Map

Chromosome 9

60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr9:110798185-110803736 bp, + strand From Ensembl annotation of GRCm38   5552 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:27410  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog

Protein SuperFamily: trypsin
Gene Tree: Prss42

Human homologs

Human Homolog		PRSS42, protease, serine, 42
NCBI Gene ID		339906
neXtProt AC		NX_Q7Z5A4
Human Synonyms		TESSP2
Human Chr (Location)		3p21.31; chr3:46871894-46875585 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(3) : Targeted(1) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	proteolysis
Component	extracellular region
Function	catalytic activity, hydrolase activity, ...

External Resources: FuncBase

Expression

cDNA source data(2)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(2) cDNA(2)
Microarray probesets(3)

Other database links

Ensembl Gene Model	ENSMUSG00000044664 (Evidence)
Entrez Gene	235628 (Evidence)
UniGene	292285
DFCI	TC1589244
DoTS	DT.94237677
NIA Mouse Gene Index	U011073
EC	3.4.21.-
Consensus CDS Project	CCDS23572.1
International Mouse Knockout Project Status	Prss42

Sequences

Length	Strain/Species
genomic	ENSMUSG00000044664	Ensembl Gene Model | MGI Sequence Detail	5552	C57BL/6J
transcript	ENSMUST00000035715	Ensembl | MGI Sequence Detail	1547	Not Applicable
polypeptide	ENSMUSP00000041088	Ensembl | MGI Sequence Detail	335	Not Applicable

All sequences(15) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(18 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR009003	Peptidase cysteine/serine, trypsin-like
InterPro	IPR001314	Peptidase S1A, chymotrypsin-type
InterPro	IPR001254	Peptidase S1/S6, chymotrypsin/Hap
InterPro	IPR018114	Peptidase S1/S6, chymotrypsin/Hap, active site
Protein Ontology	PR:000016921	testis serine protease 2

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)