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Prss42
Gene Detail
Symbol

Name
ID
Prss42
protease, serine 42
MGI:2665280
Synonyms
Tessp2
Feature Type
protein coding gene
Genetic Map
Chromosome 9
60.79 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr9:110798185-110803736 bp, + strand
From Ensembl annotation of GRCm38

  5552 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:27410  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: PRSS42
Protein SuperFamily: trypsin
Gene Tree: Prss42

Human
homologs
PRSS42, protease, serine, 42
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 339906
neXtProt AC: NX_Q7Z5A4

Human Synonyms: TESSP2

Human Chr (Location): 3p21.31; chr3:46830404-46834095 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(2) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Prss42 interacts with 115 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process germ cell development, proteolysis, ...
Component anchored component of plasma membrane, cytoplasm, ...
Function hydrolase activity, peptidase activity, ...
External Resources: FuncBase
Expression
cDNA source data(2)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(2) cDNA(2)
Microarray probesets(3)
Other database
links
Ensembl Gene Model ENSMUSG00000044664 (Evidence)
Entrez Gene 235628 (Evidence)
UniGene 292285
DFCI TC1589244
DoTS DT.94237677
NIA Mouse Gene Index U011073
EC 3.4.21.-
Consensus CDS Project CCDS23572.1
International Mouse Phenotyping Consortium Status Prss42
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044664 Ensembl Gene Model | MGI Sequence Detail 5552 C57BL/6J ±  kb
transcript ENSMUST00000035715 Ensembl | MGI Sequence Detail 1547 Not Applicable 
polypeptide ENSMUSP00000041088 Ensembl | MGI Sequence Detail 335 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(4) UniProt(2)
Polymorphisms
SNPs within 2kb(56 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001254 Peptidase S1
InterPro IPR001314 Peptidase S1A, chymotrypsin-type
InterPro IPR018114 Peptidase S1, trypsin family, active site
InterPro IPR009003 Trypsin-like cysteine/serine peptidase domain
Protein Ontology PR:000031693 serine protease 42
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:202067 Yoneda R, et al., Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis. Biol Reprod. 2013 May;88(5):118
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/18/2015
MGI 6.0
The Jackson Laboratory