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Prss42 Gene Detail
Summary
  • Symbol
    Prss42
  • Name
    protease, serine 42
  • Synonyms
    Tessp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2665280
    NCBI Gene: 235628
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110798166-110803754 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 60.79 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    61 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2665280
protein coding gene Chr9:110797248-110803754 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035356
protein coding gene Chr9:112976096-112981690 (+)
A/J MGP_AJ_G0035337
protein coding gene Chr9:108861069-108866663 (+)
AKR/J MGP_AKRJ_G0035268
protein coding gene Chr9:111567654-111573246 (+)
BALB/cJ MGP_BALBcJ_G0035332
protein coding gene Chr9:108608441-108614033 (+)
C3H/HeJ MGP_C3HHeJ_G0035040
protein coding gene Chr9:112076321-112081915 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035854
protein coding gene Chr9:116070834-116076422 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032740
protein coding gene Chr9:106076039-106081873 (+)
CAST/EiJ MGP_CASTEiJ_G0034346
protein coding gene Chr9:111869475-111875066 (+)
CBA/J MGP_CBAJ_G0035007
protein coding gene Chr9:120364900-120370499 (+)
DBA/2J MGP_DBA2J_G0035166
protein coding gene Chr9:108324229-108329821 (+)
FVB/NJ MGP_FVBNJ_G0035113
protein coding gene Chr9:107152780-107158369 (+)
LP/J MGP_LPJ_G0035245
protein coding gene Chr9:113266700-113272294 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035153
protein coding gene Chr9:121689978-121695568 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035874
protein coding gene Chr9:111910301-111915890 (+)
PWK/PhJ MGP_PWKPhJ_G0034053
protein coding gene Chr9:108570691-108576747 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033888
protein coding gene Chr9:111991639-111999803 (+)
WSB/EiJ MGP_WSBEiJ_G0034467
protein coding gene Chr9:111775812-111781414 (+)



Homology
more
  • Human Ortholog
    PRSS42, serine protease 42
  • Vertebrate Orthologs
    7
  • Human Ortholog
    PRSS42, serine protease 42
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TESSP2
  • Links
    NCBI Gene ID: 339906
    neXtProt AC: NX_Q7Z5A4
    UniProt: Q7Z5A4

  • Chr Location
    3p21.31; chr3:46830404-46834095 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044664 Ensembl Gene Model | MGI Sequence Detail 5589 C57BL/6J ±  kb
transcript ENSMUST00000035715 Ensembl | MGI Sequence Detail 1584 Not Applicable  
polypeptide ENSMUSP00000041088 Ensembl | MGI Sequence Detail 335 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:202067 Yoneda R, et al., Three testis-specific paralogous serine proteases play different roles in murine spermatogenesis and are involved in germ cell survival during meiosis. Biol Reprod. 2013 May;88(5):118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory