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Rerg
Gene Detail
Symbol

Name
ID
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
MGI:2665139
Feature Type
protein coding gene
Genetic Map
Chromosome 6
66.73 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr6:137054825-137170497 bp, - strand
From VEGA annotation of GRCm38

  115673 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:50026  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RERG
Protein SuperFamily: ras protein
Gene Tree: Rerg

Human
homologs
RERG, RAS-like, estrogen-regulated, growth inhibitor
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 85004
neXtProt AC: NX_Q96A58

Human Chr (Location): 12p12.3; chr12:15107782-15221477 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rerg interacts with 213 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process negative regulation of cell growth, negative regulation of cell proliferation, ...
Component cytoplasm, cytosol, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (36)    Tissues (4)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 36
cDNA source data(19)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA RERG ; Xenbase rerg    NEW 
Molecular
reagents
All nucleic(20) cDNA(20)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027079 (Evidence)
Ensembl Gene Model ENSMUSG00000030222 (Evidence)
Entrez Gene 232441 (Evidence)
UniGene 46233
DFCI TC1581344
DoTS DT.101367343, DT.50315509
NIA Mouse Gene Index U027981
Consensus CDS Project CCDS20663.1, CCDS51942.1
International Mouse Phenotyping Consortium Status Rerg
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027079 VEGA Gene Model | MGI Sequence Detail 115673 C57BL/6J ±  kb
transcript OTTMUST00000066962 VEGA | MGI Sequence Detail 2262 Not Applicable 
polypeptide OTTMUSP00000033627 VEGA | MGI Sequence Detail 199 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(8) UniProt(2)
Polymorphisms
SNPs within 2kb(1604 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013891 ras-related and estrogen-regulated growth inhibitor
References
(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory