About   Help   FAQ
Eras
Gene Detail
Symbol

Name
ID
Eras
ES cell-expressed Ras
MGI:2665023
Synonyms
ecat5, Ha-Ras2, HRAS2, HRasp
Feature Type
protein coding gene
Genetic Map
Chromosome X
3.58 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
ChrX:7924276-7928607 bp, - strand
From VEGA annotation of GRCm38

  4332 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:18752  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: ERAS
Gene Tree: Eras

Human
homologs
ERAS, ES cell expressed Ras
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 3266
neXtProt AC: NX_Q7Z444

Human Synonyms: HRAS2, HRASP

Human Chr (Location): Xp11.23; chrX:48826513-48829869 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(32) : Gene trapped(30) Targeted(2)
Interactions
Eras interacts with 21 markers (Mir142, Mir146, Mir146b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process signal transduction, small GTPase mediated signal transduction
Component membrane, plasma membrane
Function GTP binding, nucleotide binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (48)    Tissues (14)    Tissue x Stage Matrix (view)
Assay TypeResults
Northern blot 12
RT-PCR 36
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000018012 (Evidence)
Ensembl Gene Model ENSMUSG00000031160 (Evidence)
Entrez Gene 353283 (Evidence)
UniGene 250895
DFCI TC1590306
NIA Mouse Gene Index U039234
Consensus CDS Project CCDS29980.1
International Mouse Phenotyping Consortium Status Eras
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000018012 VEGA Gene Model | MGI Sequence Detail 4332 C57BL/6J ±  kb
transcript OTTMUST00000043501 VEGA | MGI Sequence Detail 1077 Not Applicable 
polypeptide OTTMUSP00000019552 VEGA | MGI Sequence Detail 227 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(23 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000007157 GTPase ERas
References
(Earliest) J:83420 Mitsui K, et al., The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell. 2003 May 30;113(5):631-42
(Latest) J:174767 Tang F, et al., Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
All references(31)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/21/2015
MGI 5.22
The Jackson Laboratory