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Zfp457 Gene Detail
Summary
  • Symbol
    Zfp457
  • Name
    zinc finger protein 457
  • Synonyms
    Rslcan-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2664334
    NCBI Gene: 431706
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr13:67288137-67306412 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 34.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    235 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664334
protein coding gene Chr13:67288137-67306485 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020705
protein coding gene Chr13:67432556-67447611 (-)
A/J MGP_AJ_G0020657
protein coding gene Chr13:64978142-64978923 (-)
AKR/J MGP_AKRJ_G0020635
protein coding gene Chr13:67118098-67136648 (-)
BALB/cJ MGP_BALBcJ_G0020656
protein coding gene Chr13:65448274-65460997 (-)
C3H/HeJ MGP_C3HHeJ_G0020451
protein coding gene Chr13:66744642-66756770 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021091
protein coding gene Chr13:69815259-69827630 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018663
protein coding gene Chr13:62595971-62608225 (-)
CAST/EiJ MGP_CASTEiJ_G0019970
protein coding gene Chr13:65998444-66023104 (-)
CBA/J MGP_CBAJ_G0020410
protein coding gene Chr13:72276163-72290111 (-)
DBA/2J MGP_DBA2J_G0020536
protein coding gene Chr13:64848728-64860980 (-)
FVB/NJ MGP_FVBNJ_G0020514
protein coding gene Chr13:63868087-63881777 (-)
LP/J MGP_LPJ_G0020610
protein coding gene Chr13:67673518-67685665 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020544
protein coding gene Chr13:71104504-71118647 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021133
protein coding gene Chr13:66386021-66400157 (-)
PWK/PhJ MGP_PWKPhJ_G0019721
protein coding gene Chr13:63749953-63766531 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019550
protein coding gene Chr13:63442286-63442997 (-)
WSB/EiJ MGP_WSBEiJ_G0020031
protein coding gene Chr13:66858176-66871131 (-)



Homology
more
  • Human Ortholog
    ZNF93, zinc finger protein 93
  • Vertebrate Orthologs
    4
  • Human Ortholog
    ZNF93, zinc finger protein 93
    Orthology source: HomoloGene
  • Synonyms
    HPF34, HTF34, TF34, ZNF505
  • Links
    NCBI Gene ID: 81931
    neXtProt AC: NX_P35789
    UniProt: P35789

  • Chr Location
    19p12; chr19:19900913-19935573 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 431706 NCBI Gene Model | MGI Sequence Detail 18276 C57BL/6J ±  kb
transcript NM_001003666 RefSeq | MGI Sequence Detail 2117 C57BL/6  
polypeptide NP_001003666 RefSeq | MGI Sequence Detail 647 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 13
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:86324 Krebs CJ, et al., Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Genes Dev. 2003 Nov 1;17(21):2664-74

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory