About   Help   FAQ
Fsip2 Gene Detail
Summary
  • Symbol
    Fsip2
  • Name
    fibrous sheath-interacting protein 2
  • Synonyms
    OTTMUSG00000013335
  • Feature Type
    protein coding gene
  • IDs
    MGI:2664111
    NCBI Gene: 241516
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:82943634-83008937 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 49.08 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664111
protein coding gene Chr2:82943609-83008937 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025890
protein coding gene Chr2:83601692-83669587 (+)
A/J MGP_AJ_G0025867
protein coding gene Chr2:80381144-80444773 (+)
AKR/J MGP_AKRJ_G0025836
protein coding gene Chr2:82487564-82552333 (+)
BALB/cJ MGP_BALBcJ_G0025863
protein coding gene Chr2:80553659-80621145 (+)
C3H/HeJ MGP_C3HHeJ_G0025622
protein coding gene Chr2:82775984-82842332 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026309
protein coding gene Chr2:86142590-86215552 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023712
protein coding gene Chr2:77405277-77469724 (+)
CAST/EiJ MGP_CASTEiJ_G0025084
protein coding gene Chr2:83198167-83272773 (+)
CBA/J MGP_CBAJ_G0025603
protein coding gene Chr2:89282363-89354973 (+)
DBA/2J MGP_DBA2J_G0025734
protein coding gene Chr2:79971171-80036897 (+)
FVB/NJ MGP_FVBNJ_G0025696
protein coding gene Chr2:79219276-79283890 (+)
LP/J MGP_LPJ_G0025822
protein coding gene Chr2:83455457-83524401 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025727
protein coding gene Chr2:91455604-91559174 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026365
protein coding gene Chr2:82668014-82745046 (+)
PWK/PhJ MGP_PWKPhJ_G0024827
protein coding gene Chr2:79817842-79898900 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024632
protein coding gene Chr2:82870549-82950163 (+)
WSB/EiJ MGP_WSBEiJ_G0025153
protein coding gene Chr2:83320029-83385656 (+)



Homology
more
  • Human Ortholog
    FSIP2, fibrous sheath interacting protein 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    FSIP2, fibrous sheath interacting protein 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SPGF34
  • Links
    NCBI Gene ID: 401024
    neXtProt AC: NX_Q5CZC0
    UniProt: Q5CZC0

  • Chr Location
    2q32.1; chr2:185738895-185833289 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075249 Ensembl Gene Model | MGI Sequence Detail 65304 C57BL/6J ±  kb
transcript ENSMUST00000143764 Ensembl | MGI Sequence Detail 21116 Not Applicable  
polypeptide ENSMUSP00000120314 Ensembl | MGI Sequence Detail 6995 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR038891 Fibrous sheath-interacting protein 2
    IPR031554 Fibrous sheath-interacting protein 2, C-terminal
Molecular
Reagents
less
  • All nucleic 2
    Genomic 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:3782915
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:83525 Brown PR, et al., A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum. Biol Reprod. 2003 Jun;68(6):2241-8
  • Latest
    J:269738 Guerreiro I, et al., Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan. Elife. 2016 Aug 1;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/04/2019
MGI 6.14
The Jackson Laboratory