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Cnga4 Gene Detail
Summary
  • Symbol
    Cnga4
  • Name
    cyclic nucleotide gated channel alpha 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2664099
    NCBI Gene: 233649
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:105404568-105408742 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 55.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2664099
protein coding gene Chr7:105397450-105409101 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032751
protein coding gene Chr7:108648568-108652738 (+)
A/J MGP_AJ_G0032731
protein coding gene Chr7:105811591-105815761 (+)
AKR/J MGP_AKRJ_G0032664
protein coding gene Chr7:108574815-108581686 (+)
BALB/cJ MGP_BALBcJ_G0032737
protein coding gene Chr7:105528197-105532367 (+)
C3H/HeJ MGP_C3HHeJ_G0032446
protein coding gene Chr7:108673407-108677577 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033242
protein coding gene Chr7:112965456-112969626 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030226
protein coding gene Chr7:107790514-107794695 (+)
CAST/EiJ MGP_CASTEiJ_G0031776
protein coding gene Chr7:100496533-100501439 (+)
CBA/J MGP_CBAJ_G0032420
protein coding gene Chr7:116746424-116750594 (+)
DBA/2J MGP_DBA2J_G0032573
protein coding gene Chr7:104082515-104086685 (+)
FVB/NJ MGP_FVBNJ_G0032526
protein coding gene Chr7:103888240-103892411 (+)
LP/J MGP_LPJ_G0032664
protein coding gene Chr7:110052322-110056492 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032558
protein coding gene Chr7:118355535-118359705 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033263
protein coding gene Chr7:107624839-107629010 (+)
PWK/PhJ MGP_PWKPhJ_G0031489
protein coding gene Chr7:97009408-97018256 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031338
protein coding gene Chr7:94743031-94747211 (+)
WSB/EiJ MGP_WSBEiJ_G0031893
protein coding gene Chr7:108268408-108272579 (+)



Homology
more
  • Human Ortholog
    CNGA4, cyclic nucleotide gated channel alpha 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CNGA4, cyclic nucleotide gated channel alpha 4
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CNCA2, CNG4, CNG-4, CNG5, CNGB2, OCNC2, OCNCb, OCNCBETA
  • Links
    NCBI Gene ID: 1262
    neXtProt AC: NX_Q8IV77
    UniProt: Q8IV77

  • Chr Location
    11p15.4; chr11:6234774-6245924 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Inactivation of this gene results in odor adaptation defects.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030897 Ensembl Gene Model | MGI Sequence Detail 4175 C57BL/6J ±  kb
transcript ENSMUST00000033187 Ensembl | MGI Sequence Detail 2484 Not Applicable  
polypeptide ENSMUSP00000033187 Ensembl | MGI Sequence Detail 575 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 2
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 37
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:179991 Cisneros-Mejorado A, et al., cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation. FEBS Lett. 2012 Jan 20;586(2):149-53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/04/2018
MGI 6.13
The Jackson Laboratory