Kcng3
Gene Detail

Symbol Name ID

Kcng3 potassium voltage-gated channel, subfamily G, member 3 MGI:2663923

Synonyms

Kv10.1a, Kv10.1b, KV6.3

Feature Type

protein coding gene

Genetic Map

Chromosome 17

53.64 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr17:83585957-83631895 bp, - strand From NCBI annotation of GRCm38   45939 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:15168  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: potassium voltage-gated channel, alpha subunit, subfamilies A/C/D/F/G/S
Gene Tree: Kcng3

Human homologs

Human Homolog		KCNG3, potassium voltage-gated channel, subfamily G, member 3
NCBI Gene ID		170850
neXtProt AC		NX_Q8TAE7
Human Synonyms		KV10.1, KV6.3
Human Chr (Location)		2p21; chr2:42669157-42721237 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(11) : Targeted(2) Gene trapped(9)

Gene Ontology (GO) classifications

All GO classifications: (21 annotations)

Process	ion transport, potassium ion transmembrane transport, ...
Component	cytoplasm, endoplasmic reticulum, ...
Function	delayed rectifier potassium channel activity, ion channel activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (21)    Tissues (4)    Images (17)
Theiler Stages: 23

Assay Type	Results
RNA in situ	21

cDNA source data(1)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(3) cDNA(1) Other(2)
Microarray probesets(1)

Other database links

Ensembl Gene Model	ENSMUSG00000045053 (Evidence)
Entrez Gene	225030 (Evidence)
UniGene	223506
DoTS	DT.101349852, DT.101349853
NIA Mouse Gene Index	U038100
Consensus CDS Project	CCDS28996.1
International Mouse Knockout Project Status	Kcng3

Sequences

Length	Strain/Species
genomic	225030	NCBI Gene Model | MGI Sequence Detail	45939	C57BL/6J
transcript	NM_153512	RefSeq | MGI Sequence Detail	3356	Not Specified
polypeptide	P59053	UniProt | EBI | MGI Sequence Detail	433	Not Applicable

All sequences(14) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(182 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR011333	BTB/POZ fold
InterPro	IPR000210	BTB/POZ-like
InterPro	IPR005821	Ion transport domain
InterPro	IPR003131	Potassium channel tetramerisation-type BTB domain
InterPro	IPR003968	Potassium channel, voltage dependent, Kv
InterPro	IPR003971	Potassium channel, voltage dependent, Kv9
InterPro	IPR003091	Voltage-dependent potassium channel
Protein Ontology	PR:000000788	voltage-gated potassium channel KCNG3

Graphical View of Protein Domain Structure

References

(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(28)