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Kcng3 Gene Detail
Summary
  • Symbol
    Kcng3
  • Name
    potassium voltage-gated channel, subfamily G, member 3
  • Synonyms
    Kv10.1a, Kv10.1b, KV6.3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2663923
    NCBI Gene: 225030
Location & Maps
more
  • Sequence Map
    Chr17:83585957-83631895 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      45939 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    KCNG3, potassium channel, voltage gated modifier subfamily G, member 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KCNG3, potassium channel, voltage gated modifier subfamily G, member 3
    Orthology source: HGNC, HomoloGene
  • Synonyms
    KV10.1, KV6.3
  • Links
    NCBI Gene ID: 170850
    neXtProt AC: NX_Q8TAE7

  • Chr Location
    2p21; chr2:42442017-42494097 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    13
  • Gene trapped
    9
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045053 Ensembl Gene Model | MGI Sequence Detail 45939 C57BL/6J ±  kb
transcript ENSMUST00000051482 Ensembl | MGI Sequence Detail 3356 Not Applicable  
polypeptide ENSMUSP00000054910 Ensembl | MGI Sequence Detail 433 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    389 from dbSNP Build 137
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000000788 voltage-gated potassium channel KCNG3
  • InterPro Domains
    IPR000210 BTB/POZ domain
    IPR005821 Ion transport domain
    IPR003131 Potassium channel tetramerisation-type BTB domain
    IPR003968 Potassium channel, voltage dependent, Kv
    IPR003971 Potassium channel, voltage dependent, Kv9
    IPR011333 SKP1/BTB/POZ domain
    IPR027359 Voltage-dependent channel, four helix bundle domain
    IPR028325 Voltage-gated potassium channel
Molecular
Reagents
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  • All nucleic 3
    cDNA 1
    Other 2

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory