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Hcfc1r1 Gene Detail
Summary
  • Symbol
    Hcfc1r1
  • Name
    host cell factor C1 regulator 1 (XPO1-dependent)
  • Feature Type
    protein coding gene
  • IDs
    MGI:2663619
    NCBI Gene: 353502
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:23892570-23894201 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 11.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    13 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2663619
protein coding gene Chr17:23892570-23894498 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023262
protein coding gene Chr17:22588971-22590602 (+)
A/J MGP_AJ_G0023222
protein coding gene Chr17:21939226-21940857 (+)
AKR/J MGP_AKRJ_G0023192
protein coding gene Chr17:22015564-22017195 (+)
BALB/cJ MGP_BALBcJ_G0023227
protein coding gene Chr17:22153658-22155289 (+)
C3H/HeJ MGP_C3HHeJ_G0022987
protein coding gene Chr17:22377068-22378699 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023670
protein coding gene Chr17:23570469-23572100 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021151
protein coding gene Chr17:19508280-19509884 (+)
CAST/EiJ MGP_CASTEiJ_G0022493
protein coding gene Chr17:22209919-22211550 (+)
CBA/J MGP_CBAJ_G0022963
protein coding gene Chr17:24380845-24382476 (+)
DBA/2J MGP_DBA2J_G0023095
protein coding gene Chr17:21567524-21569155 (+)
FVB/NJ MGP_FVBNJ_G0023062
protein coding gene Chr17:21292176-21293807 (+)
LP/J MGP_LPJ_G0023169
protein coding gene Chr17:22847049-22848680 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023081
protein coding gene Chr17:24143351-24144982 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023709
protein coding gene Chr17:22308844-22310475 (+)
PWK/PhJ MGP_PWKPhJ_G0022241
protein coding gene Chr17:20352578-20354209 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022061
protein coding gene Chr17:20332699-20334328 (+)
WSB/EiJ MGP_WSBEiJ_G0022556
protein coding gene Chr17:22364032-22365663 (+)



Homology
more
  • Human Ortholog
    HCFC1R1, host cell factor C1 regulator 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HCFC1R1, host cell factor C1 regulator 1
  • Synonyms
    HPIP
  • Links
    NCBI Gene ID: 54985
    neXtProt AC: NX_Q9NWW0
    UniProt: Q9NWW0

  • Chr Location
    16p13.3; chr16:3022620-3024286 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023904 Ensembl Gene Model | MGI Sequence Detail 1632 C57BL/6J ±  kb
transcript ENSMUST00000024697 Ensembl | MGI Sequence Detail 946 Not Applicable  
polypeptide ENSMUSP00000024697 Ensembl | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 2
    cDNA 4

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:80187 Mahajan SS, et al., Interaction of HCF-1 with a Cellular Nuclear Export Factor. J Biol Chem. 2002 Nov 15;277(46):44292-9
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory