About   Help   FAQ
Kbtbd8 Gene Detail
Summary
  • Symbol
    Kbtbd8
  • Name
    kelch repeat and BTB (POZ) domain containing 8
  • Synonyms
    mKIAA1842, SSEC51, SSEC 51, SSEC-51, Takrp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2661430
    NCBI Gene: 243574
Location & Maps
more
  • Sequence Map
    Chr6:95117240-95129790 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12551 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    KBTBD8, kelch repeat and BTB domain containing 8
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KBTBD8, kelch repeat and BTB domain containing 8
    Orthology source: HGNC, HomoloGene
  • Synonyms
    TAKRP, TA-KRP
  • Links
    NCBI Gene ID: 84541
    neXtProt AC: NX_Q8NFY9

  • Chr Location
    3p14; chr3:66998303-67011211 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    4
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Kbtbd8
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029697 VEGA Gene Model | MGI Sequence Detail 12551 C57BL/6J ±  kb
transcript OTTMUST00000073683 VEGA | MGI Sequence Detail 4869 Not Applicable  
polypeptide OTTMUSP00000038182 VEGA | MGI Sequence Detail 599 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    69 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 66

    Microarray probesets 6
Other
Accession IDs
less
MGI:2141580
References
more
  • Summaries
    All 29
    Developmental Gene Expression 4
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/17/2016
MGI 6.03
The Jackson Laboratory