About   Help   FAQ
Snx13
Gene Detail
 Symbol
Name
ID
Snx13
sorting nexin 13
MGI:2661416
Synonyms mKIAA0713, RGS-PX1
Feature Type protein coding gene
Genetic Map
Chromosome 12
15.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr12:35047189-35147469 bp, + strand
From Ensembl annotation of GRCm38

  100281 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41011  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: sorting nexin, SNX 13 type
Gene Tree: Snx13

Human
homologs
Human Homolog SNX13, sorting nexin 13
NCBI Gene ID 23161
neXtProt AC  NX_Q9Y5W8
Human Synonyms  RGS-PX1
Human Chr (Location)  7p21.1; chr7:17790761-17940518 (-)  GRCh38
Alleles
and
phenotypes
All alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous null mice are growth retarded and die at midgestation with defects in neural tube closure, vasculogenesis and placental development. Mutant visceral yolk sac endoderm cells exhibit altered endocytic compartments, abundant autophagic vacuoles and mislocalization of endocytic markers.
 
Phenotype Images(2)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process intracellular protein transport, negative regulation of signal transduction, ...
Component early endosome, endosome, ...
Function lipid binding, phosphatidylinositol binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (4)    Tissues (1)    Images (1)
Theiler Stages: 17
Assay TypeResults
RT-PCR 4
cDNA source data(69)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(70) cDNA(69) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000020590 (Evidence)
Entrez Gene217463 (Evidence)
UniGene213991
DFCITC1579063, TC1651339
DoTSDT.101190423, DT.101383385, DT.102556260, DT.527927
NIA Mouse Gene IndexU043270
Consensus CDS ProjectCCDS56837.1
International Mouse Knockout Project StatusSnx13
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020590 Ensembl Gene Model | MGI Sequence Detail 100281 C57BL/6J ±  kb
transcript ENSMUST00000048519 Ensembl | MGI Sequence Detail 6218 Not Applicable 
polypeptide ENSMUSP00000038430 Ensembl | MGI Sequence Detail 958 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(10) UniProt(9)
Polymorphisms SNPs within 2kb(1020 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003114 Phox-associated domain
InterPro IPR001683 Phox homologous domain
InterPro IPR013996 PX-associated, sorting nexin 13
InterPro IPR000342 Regulator of G protein signalling
InterPro IPR016137 Regulator of G protein signalling superfamily
InterPro IPR013937 Sorting nexin, C-terminal
Protein Ontology PR:000015362 sorting nexin-13
References (Earliest) J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/15/2014
MGI 5.18
The Jackson Laboratory