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Prss33 Gene Detail
Summary
  • Symbol
    Prss33
  • Name
    protease, serine 33
  • Synonyms
    Eos, mT6, tryptase-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2661234
    NCBI Gene: 353130
Location & Maps
more
  • Sequence Map
    Chr17:23833360-23836056 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2697 bp   ±  kb flank

  • Genome Browsers
Homology
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  • Human Ortholog
    PRSS33, protease, serine 33
  • Vertebrate Orthologs
    5
  • Human Ortholog
    PRSS33, protease, serine 33
    Orthology source: HomoloGene
  • Synonyms
    EOS
  • Links
    NCBI Gene ID: 260429
    neXtProt AC: NX_Q8NF86

  • Chr Location
    16p13.3; chr16:2783953-2787607 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035218 VEGA Gene Model | MGI Sequence Detail 2697 C57BL/6J ±  kb
transcript OTTMUST00000089733 VEGA | MGI Sequence Detail 1360 Not Applicable  
polypeptide OTTMUSP00000049073 VEGA | MGI Sequence Detail 277 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    22 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013326 serine protease 33
  • EC
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
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  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:86752 Wong GW, et al., Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns. J Biol Chem. 2004 Jan 23;279(4):2438-52
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory