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Prss33 Gene Detail
Summary
  • Symbol
    Prss33
  • Name
    protease, serine 33
  • Synonyms
    Eos, mT6, tryptase-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2661234
    NCBI Gene: 353130
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr17:23833347-23836056 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 12.08 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    22 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2661234
protein coding gene Chr17:23833338-23836693 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023274
protein coding gene Chr17:22763681-22766377 (-)
A/J MGP_AJ_G0023234
protein coding gene Chr17:22104425-22107121 (-)
AKR/J MGP_AKRJ_G0023204
protein coding gene Chr17:22183976-22186672 (-)
BALB/cJ MGP_BALBcJ_G0023239
protein coding gene Chr17:22313364-22316060 (-)
C3H/HeJ MGP_C3HHeJ_G0022999
protein coding gene Chr17:22554473-22557169 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023682
protein coding gene Chr17:23745850-23748546 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021163
protein coding gene Chr17:19662813-19665535 (-)
CAST/EiJ MGP_CASTEiJ_G0022505
protein coding gene Chr17:22376169-22378865 (-)
CBA/J MGP_CBAJ_G0022975
protein coding gene Chr17:24569536-24572232 (-)
DBA/2J MGP_DBA2J_G0023107
protein coding gene Chr17:21733340-21736036 (-)
FVB/NJ MGP_FVBNJ_G0023074
protein coding gene Chr17:21453092-21455788 (-)
LP/J MGP_LPJ_G0023181
protein coding gene Chr17:23027743-23030439 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023093
protein coding gene Chr17:24311051-24313747 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023721
protein coding gene Chr17:22478801-22481497 (-)
PWK/PhJ MGP_PWKPhJ_G0022253
protein coding gene Chr17:20515420-20518116 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022073
protein coding gene Chr17:20493972-20496655 (-)
WSB/EiJ MGP_WSBEiJ_G0022568
protein coding gene Chr17:22531229-22533925 (-)



Homology
more
  • Human Ortholog
    PRSS33, serine protease 33
  • Vertebrate Orthologs
    5
  • Human Ortholog
    PRSS33, serine protease 33
    Orthology source: HomoloGene, HGNC
  • Synonyms
    EOS
  • Links
    NCBI Gene ID: 260429
    neXtProt AC: NX_Q8NF86
    UniProt: Q8NF86

  • Chr Location
    16p13.3; chr16:2783953-2787759 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049620 Ensembl Gene Model | MGI Sequence Detail 2710 C57BL/6J ±  kb
transcript ENSMUST00000059906 Ensembl | MGI Sequence Detail 1373 Not Applicable  
polypeptide ENSMUSP00000059491 Ensembl | MGI Sequence Detail 277 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:86752 Wong GW, et al., Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns. J Biol Chem. 2004 Jan 23;279(4):2438-52
  • Latest
    J:240536 Martin-Ibanez R, et al., Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory