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Gmppb
Gene Detail
 Symbol
Name
ID
Gmppb
GDP-mannose pyrophosphorylase B
MGI:2660880
Feature Type protein coding gene
Genetic Map
Chromosome 9
59.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:108049269-108052801 bp, + strand
From VEGA annotation of GRCm38

  3533 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5578  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: mannose-1-phosphate guanylyltransferase
Gene Tree: Gmppb

Human
homologs
Human Homolog GMPPB, GDP-mannose pyrophosphorylase B
NCBI Gene ID 29925
neXtProt AC  NX_Q9Y5P6
Human Synonyms  MDDGA14, MDDGB14, MDDGC14
Human Chr (Location)  3p21.31; chr3:49721476-49723974 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human GMPPB
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Gmppb interacts with 185 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process biosynthetic process
Component cytoplasm, mitochondrion
Function GTP binding, mannose-1-phosphate guanylyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (97)    Tissues (97)    Images (18)
Theiler Stages: 22
Assay TypeResults
RNA in situ 97
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000016525 (Evidence)
Ensembl Gene ModelENSMUSG00000070284 (Evidence)
Entrez Gene331026 (Evidence)
EC2.7.7.13
Consensus CDS ProjectCCDS23515.1
International Mouse Knockout Project StatusGmppb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016525 VEGA Gene Model | MGI Sequence Detail 3533 C57BL/6J ±  kb
transcript OTTMUST00000039936 VEGA | MGI Sequence Detail 2655 Not Applicable 
polypeptide OTTMUSP00000017806 VEGA | MGI Sequence Detail 360 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(1)
Polymorphisms SNPs within 2kb(39 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001451 Bacterial transferase hexapeptide repeat
InterPro IPR018357 Hexapeptide transferase, conserved site
InterPro IPR005835 Nucleotidyl transferase
Protein Ontology PR:000008076 mannose-1-phosphate guanyltransferase beta
References (Earliest) J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
(Latest) J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511
All references(28)
Other
accession IDs
MGI:2143016

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory