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Gmppb Gene Detail
Summary
  • Symbol
    Gmppb
  • Name
    GDP-mannose pyrophosphorylase B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660880
    NCBI Gene: 331026
  • Gene Overview
    MyGene.info: GMPPB
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108049267-108051936 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    33 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2660880
protein coding gene Chr9:108049242-108052801 (.)
129S1/SvImJ MGP_129S1SvImJ_G0035282
protein coding gene Chr9:109975439-109978991 (+)
A/J MGP_AJ_G0035261
protein coding gene Chr9:105955034-105958593 (+)
AKR/J MGP_AKRJ_G0035193
protein coding gene Chr9:108597696-108601249 (+)
BALB/cJ MGP_BALBcJ_G0035255
protein coding gene Chr9:105650725-105654284 (+)
C3H/HeJ MGP_C3HHeJ_G0034965
protein coding gene Chr9:108996336-108999895 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035775
protein coding gene Chr9:112949072-112952631 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032673
protein coding gene Chr9:103388891-103392456 (+)
CAST/EiJ MGP_CASTEiJ_G0034276
protein coding gene Chr9:108955141-108958702 (+)
CBA/J MGP_CBAJ_G0034933
protein coding gene Chr9:116945499-116949066 (+)
DBA/2J MGP_DBA2J_G0035094
protein coding gene Chr9:105409454-105413007 (+)
FVB/NJ MGP_FVBNJ_G0035042
protein coding gene Chr9:104177845-104181404 (+)
LP/J MGP_LPJ_G0035170
protein coding gene Chr9:110166170-110168810 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035081
protein coding gene Chr9:118533787-118537346 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035796
protein coding gene Chr9:108876988-108880541 (+)
PWK/PhJ MGP_PWKPhJ_G0033983
protein coding gene Chr9:105731276-105734843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033818
protein coding gene Chr9:108938364-108941931 (+)
WSB/EiJ MGP_WSBEiJ_G0034397
protein coding gene Chr9:108755409-108758962 (+)



Homology
more
  • Human Ortholog
    GMPPB, GDP-mannose pyrophosphorylase B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GMPPB, GDP-mannose pyrophosphorylase B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LGMDR19, MDDGA14, MDDGB14, MDDGC14
  • Links
    NCBI Gene ID: 29925
    neXtProt AC: NX_Q9Y5P6
    UniProt: Q9Y5P6

  • Chr Location
    3p21.31; chr3:49721476-49723974 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human GMPPB associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 331026 NCBI Gene Model | MGI Sequence Detail 2670 C57BL/6J ±  kb
transcript NM_177910 RefSeq | MGI Sequence Detail 1799 Not Specified  
polypeptide Q8BTZ7 UniProt | EBI | MGI Sequence Detail 360 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143016
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory