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Gmppb Gene Detail
Summary
  • Symbol
    Gmppb
  • Name
    GDP-mannose pyrophosphorylase B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660880
    NCBI Gene: 331026
  • Gene Overview
    MyGene.info: GMPPB
Location & Maps
more
  • Sequence Map
    Chr9:108049242-108052801 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3560 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.07 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    GMPPB, GDP-mannose pyrophosphorylase B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GMPPB, GDP-mannose pyrophosphorylase B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    MDDGA14, MDDGB14, MDDGC14
  • Links
    NCBI Gene ID: 29925
    neXtProt AC: NX_Q9Y5P6

  • Chr Location
    3p21.31; chr3:49721476-49723974 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    3 with human GMPPB associations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000016525 VEGA Gene Model | MGI Sequence Detail 3560 C57BL/6J ±  kb
transcript OTTMUST00000039937 VEGA | MGI Sequence Detail 1429 Not Applicable  
polypeptide OTTMUSP00000017807 VEGA | MGI Sequence Detail 360 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    39 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000008076 mannose-1-phosphate guanyltransferase beta
  • EC
  • InterPro Domains
    IPR001451 Hexapeptide repeat
    IPR018357 Hexapeptide transferase, conserved site
    IPR029044 Nucleotide-diphospho-sugar transferases
    IPR005835 Nucleotidyl transferase domain
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143016
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:149737 Sansom SN, et al., The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet. 2009 Jun;5(6):e1000511

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory