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Gucy1b2 Gene Detail
Summary
  • Symbol
    Gucy1b2
  • Name
    guanylate cyclase 1, soluble, beta 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660873
    NCBI Gene: 239134
Location & Maps
more
  • Sequence Map
    Chr14:62392676-62456289 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      63614 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    GUCY1B2, guanylate cyclase 1, soluble, beta 2 (pseudogene)
  • Vertebrate Orthologs
    7
  • Human Ortholog
    GUCY1B2, guanylate cyclase 1, soluble, beta 2 (pseudogene)
    Orthology source: HGNC
  • Synonyms
    GC-SB2
  • Links
    NCBI Gene ID: 2974
    neXtProt AC: NX_O75343

  • Chr Location
    13q14.3; chr13:50994511-51066157 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Gucy1b2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019627 VEGA Gene Model | MGI Sequence Detail 63614 C57BL/6J ±  kb
transcript OTTMUST00000046900 VEGA | MGI Sequence Detail 2711 Not Applicable  
polypeptide OTTMUSP00000021192 VEGA | MGI Sequence Detail 824 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    521 from dbSNP Build 142
Protein
Information
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  • UniProt
    7 Sequences
  • EC
  • InterPro Domains
    IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
    IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
    IPR011645 Haem NO binding associated
    IPR011644 Heme-NO binding
    IPR024096 NO signalling/Golgi transport ligand-binding domain
    IPR029787 Nucleotide cyclase
Molecular
Reagents
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  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:218085 Omura M, et al., Trpc2-expressing sensory neurons in the mouse main olfactory epithelium of type B express the soluble guanylate cyclase Gucy1b2. Mol Cell Neurosci. 2015 Feb 19;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory