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C1rl Gene Detail
Summary
  • Symbol
    C1rl
  • Name
    complement component 1, r subcomponent-like
  • Synonyms
    C1rl1, C1r-LP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2660692
    NCBI Gene: 232371
Location & Maps
more
  • Sequence Map
    Chr6:124493113-124510643 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17531 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 59.16 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    C1RL, complement C1r subcomponent like
  • Vertebrate Orthologs
    7
  • Human Ortholog
    C1RL, complement C1r subcomponent like
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1RL1, C1r-LP, C1RLP, CLSPa
  • Links
    NCBI Gene ID: 51279
    neXtProt AC: NX_Q9NZP8

  • Chr Location
    12p13.31; chr12:7093668-7109278 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Gene trapped
    1
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022316 VEGA Gene Model | MGI Sequence Detail 17531 C57BL/6J ±  kb
transcript OTTMUST00000139860 VEGA | MGI Sequence Detail 3010 Not Applicable  
polypeptide OTTMUSP00000073361 VEGA | MGI Sequence Detail 482 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    85 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:83023 Circolo A, et al., A novel murine complement-related gene encoding a C1r-like serum protein. Mol Immunol. 2003 May;39(14):899-906
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory