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Wasf3 Gene Detail
Summary
  • Symbol
    Wasf3
  • Name
    WAS protein family, member 3
  • Synonyms
    Wave3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2658986
    NCBI Gene: 245880
  • Gene Overview
    MyGene.info: WASF3
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:146384990-146473615 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 85.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    408 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2658986
protein coding gene Chr5:146384985-146473615 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030376
protein coding gene Chr5:151964254-152056357 (+)
A/J MGP_AJ_G0030349
protein coding gene Chr5:145542849-145627078 (+)
AKR/J MGP_AKRJ_G0030276
protein coding gene Chr5:149975073-150073465 (+)
BALB/cJ MGP_BALBcJ_G0030358
protein coding gene Chr5:146749654-146836048 (+)
C3H/HeJ MGP_C3HHeJ_G0030072
protein coding gene Chr5:150934919-151021839 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030813
protein coding gene Chr5:157531533-157619685 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028026
protein coding gene Chr5:139958607-140046523 (+)
CAST/EiJ MGP_CASTEiJ_G0029474
protein coding gene Chr5:150437480-150529844 (+)
CBA/J MGP_CBAJ_G0030050
protein coding gene Chr5:164075333-164177368 (+)
DBA/2J MGP_DBA2J_G0030194
protein coding gene Chr5:145207030-145304434 (+)
FVB/NJ MGP_FVBNJ_G0030148
protein coding gene Chr5:144411447-144498758 (+)
LP/J MGP_LPJ_G0030281
protein coding gene Chr5:152632741-152716734 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030184
protein coding gene Chr5:166424124-166517224 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030843
protein coding gene Chr5:149884199-149979677 (+)
PWK/PhJ MGP_PWKPhJ_G0029188
protein coding gene Chr5:144285255-144375400 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029024
protein coding gene Chr5:147146565-147246553 (+)
WSB/EiJ MGP_WSBEiJ_G0029551
protein coding gene Chr5:150701738-150790915 (+)



Homology
more
  • Human Ortholog
    WASF3, WAS protein family member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    WASF3, WAS protein family member 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Brush-1, SCAR3, WAVE3
  • Links
    NCBI Gene ID: 10810
    neXtProt AC: NX_Q9UPY6
    UniProt: Q9UPY6

  • Chr Location
    13q12.13; chr13:26557703-26688945 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for a knock-out allele exhibit normal platelet physiology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 245880 NCBI Gene Model | MGI Sequence Detail 88626 C57BL/6J ±  kb
transcript NM_145155 RefSeq | MGI Sequence Detail 2685 C57BL/6  
polypeptide Q8VHI6 UniProt | EBI | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    Genomic 1
    cDNA 17
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:83138 Sossey-Alaoui K, et al., Genomic organization and expression profile of the human and mouse WAVE gene family. Mamm Genome. 2003 May;14(5):314-22
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory