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Wasf3 Gene Detail
Summary
  • Symbol
    Wasf3
  • Name
    WAS protein family, member 3
  • Synonyms
    Wave3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2658986
    NCBI Gene: 245880
  • Gene Overview
    MyGene.info: WASF3
Location & Maps
more
  • Sequence Map
    Chr5:146384985-146473615 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      88631 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    WASF3, WAS protein family member 3
  • Vertebrate Orthologs
    9
  • Human Ortholog
    WASF3, WAS protein family member 3
    Orthology source: HomoloGene
  • Synonyms
    Brush-1, SCAR3, WAVE3
  • Links
    NCBI Gene ID: 10810
    neXtProt AC: NX_Q9UPY6

  • Chr Location
    13q12; chr13:26557703-26688945 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Mice homozygous for a knock-out allele exhibit normal platelet physiology.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025851 VEGA Gene Model | MGI Sequence Detail 88631 C57BL/6J ±  kb
transcript OTTMUST00000136575 VEGA | MGI Sequence Detail 5196 Not Applicable  
polypeptide OTTMUSP00000072057 VEGA | MGI Sequence Detail 501 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    408 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000017374 Wiskott-Aldrich syndrome protein family member 3
  • InterPro Domains
    IPR028288 SCAR/WAVE family
    IPR003124 WH2 domain
Molecular
Reagents
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  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 32
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:83138 Sossey-Alaoui K, et al., Genomic organization and expression profile of the human and mouse WAVE gene family. Mamm Genome. 2003 May;14(5):314-22
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory