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Rtl1 Gene Detail
Summary
  • Symbol
    Rtl1
  • Name
    retrotransposon Gaglike 1
  • Synonyms
    Mar, Mart1, Mor1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2656842
    NCBI Gene: 353326
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:109589193-109600330 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 60.38 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    44 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2656842
protein coding gene Chr12:109564900-109604418 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020115
protein coding gene Chr12:111817787-111830332 (-)
A/J MGP_AJ_G0020069
protein coding gene Chr12:107512359-107523141 (-)
AKR/J MGP_AKRJ_G0020045
protein coding gene Chr12:110649313-110660461 (-)
BALB/cJ MGP_BALBcJ_G0020055
protein coding gene Chr12:107985757-107996648 (-)
C3H/HeJ MGP_C3HHeJ_G0019857
protein coding gene Chr12:111090725-111102965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020500
protein coding gene Chr12:115237378-115248421 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018112
protein coding gene Chr12:104038554-104050132 (-)
CAST/EiJ MGP_CASTEiJ_G0019399
protein coding gene Chr12:106042228-106053111 (-)
CBA/J MGP_CBAJ_G0019824
protein coding gene Chr12:119776793-119787701 (-)
DBA/2J MGP_DBA2J_G0019941
protein coding gene Chr12:107067353-107078217 (-)
FVB/NJ MGP_FVBNJ_G0019926
protein coding gene Chr12:105858017-105868928 (-)
LP/J MGP_LPJ_G0020016
protein coding gene Chr12:111644957-111658942 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019964
protein coding gene Chr12:122930849-122945010 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020529
protein coding gene Chr12:110129192-110142037 (-)
PWK/PhJ MGP_PWKPhJ_G0019158
protein coding gene Chr12:101675613-101686866 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018962
protein coding gene Chr12:104299936-104311901 (-)
WSB/EiJ MGP_WSBEiJ_G0019456
protein coding gene Chr12:111044022-111056107 (-)



Homology
more
  • Human Ortholog
    RTL1, retrotransposon Gag like 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RTL1, retrotransposon Gag like 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HUR1, Mar1, MART1, PEG11, SIRH2
  • Links
    NCBI Gene ID: 388015
    neXtProt AC: NX_A6NKG5
    UniProt: A6NKG5

  • Chr Location
    14q32.2; chr14:100880655-100884847 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice heterozygous for a paternally inherited knock-out allele exhibit fetal/neonatal lethality associated with underdevelopment of the placenta. Mice heteroygous for a maternally inherited knock-out allele exhibit neonatal lethality and decreased survival associated with placental overdevelopment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000085925 Ensembl Gene Model | MGI Sequence Detail 11138 C57BL/6J ±  kb
    transcript ENSMUST00000149046 Ensembl | MGI Sequence Detail 6358 Not Applicable  
    polypeptide ENSMUSP00000115957 Ensembl | MGI Sequence Detail 1744 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 5
      Primer pair 3
      Other 3

      Microarray probesets 2
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 22
      Gene Ontology 1
      Phenotypes 2
    • Earliest
      J:84074 Seitz H, et al., Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene. Nat Genet. 2003 Jul;34(3):261-2
    • Latest
      J:281273 Zhu W, et al., Meg3-DMR, not the Meg3 gene, regulates imprinting of the Dlk1-Dio3 locus. Dev Biol. 2019 Nov 1;455(1):10-18

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    02/11/2020
    MGI 6.14
    The Jackson Laboratory