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Ang4
Gene Detail
 Symbol
Name
ID
Ang4
angiogenin, ribonuclease A family, member 4
MGI:2656551
Synonyms Rnase5d
Feature Type protein coding gene
Genetic Map
Chromosome 14
26.66 cM, cytoband B-C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:51763878-51773590 bp, - strand
From VEGA annotation of GRCm38

  9713 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:135633  Vertebrate Homology Class
1 mouse; 3 cattle; 2 zebrafish

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Ang4

Alleles
and
phenotypes
All alleles(1) : Gene trapped(1)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process angiogenesis, antibacterial humoral response, ...
Component basement membrane, cytoplasmic vesicle, ...
Function endonuclease activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(19)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000036425 (Evidence)
Ensembl Gene ModelENSMUSG00000060615 (Evidence)
Entrez Gene219033 (Evidence)
UniGene343899
DFCITC1584304
DoTSDT.94263999
NIA Mouse Gene IndexU049200
EC3.1.27.-
PDB2J4T
Consensus CDS ProjectCCDS36911.1
International Mouse Knockout Project StatusAng4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036425 VEGA Gene Model | MGI Sequence Detail 9713 C57BL/6J ±  kb
transcript OTTMUST00000093335 VEGA | MGI Sequence Detail 709 Not Applicable 
polypeptide OTTMUSP00000051748 VEGA | MGI Sequence Detail 144 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(241 from dbSNP Build 137)    SNPs within 2kb including multiple locations(261)
Protein-related
information
ResourceIDDescription
InterPro IPR001427 Ribonuclease A
InterPro IPR023411 Ribonuclease A, active site
InterPro IPR023412 Ribonuclease A-domain
Protein Ontology PR:000033303 angiogenin-4
References (Earliest) J:82368 Hooper LV, et al., Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol. 2003 Mar;4(3):269-73
(Latest) J:154852 Gregorieff A, et al., The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology. 2009 Oct;137(4):1333-45.e1-3
All references(28)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory