Ang4
Gene Detail

Symbol Name ID

Ang4 angiogenin, ribonuclease A family, member 4 MGI:2656551

Synonyms

Rnase5d

Feature Type

protein coding gene

Genetic Map

Chromosome 14

26.66 cM, cytoband B-C1
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr14:51763878-51773590 bp, - strand From VEGA annotation of GRCm38   9713 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:117946  Vertebrate Homology Class
4 mouse

Protein SuperFamily: pyrimidine-specific ribonuclease/angiogenin
Gene Tree: Ang4

Alleles and phenotypes

All alleles(1) : Gene trapped(1)

Gene Ontology (GO) classifications

All GO classifications: (19 annotations)

Process	angiogenesis, antibacterial humoral response, ...
Component	basement membrane, cytoplasmic vesicle, ...
Function	endonuclease activity, hydrolase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
cDNA source data(19)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(19) cDNA(19)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000036425 (Evidence)
Ensembl Gene Model	ENSMUSG00000060615 (Evidence)
Entrez Gene	219033 (Evidence)
UniGene	343899
DFCI	TC1584304
DoTS	DT.94263999
NIA Mouse Gene Index	U049200
EC	3.1.27.-
PDB	2J4T
Consensus CDS Project	CCDS36911.1
International Mouse Knockout Project Status	Ang4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000036425	VEGA Gene Model | MGI Sequence Detail	9713	C57BL/6J
transcript	OTTMUST00000093335	VEGA | MGI Sequence Detail	709	Not Applicable
polypeptide	OTTMUSP00000051748	VEGA | MGI Sequence Detail	144	Not Applicable

All sequences(22) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(86 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001427	Ribonuclease A
InterPro	IPR023411	Ribonuclease A, active site
InterPro	IPR023412	Ribonuclease A-domain
Protein Ontology	PR:000033303	angiogenin-4

References

(Earliest) J:82368 Hooper LV, et al., Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nat Immunol. 2003 Mar;4(3):269-73
(Latest) J:154852 Gregorieff A, et al., The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology. 2009 Oct;137(4):1333-45.e1-3
All references(28)