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Asb14 Gene Detail
Summary
  • Symbol
    Asb14
  • Name
    ankyrin repeat and SOCS box-containing 14
  • Feature Type
    protein coding gene
  • IDs
    MGI:2655107
    NCBI Gene: 142687
Location & Maps
more
  • Sequence Map
    Chr14:26894557-26915258 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20702 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 16.09 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ASB14, ankyrin repeat and SOCS box containing 14
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ASB14, ankyrin repeat and SOCS box containing 14
    Orthology source: HomoloGene
  • Links
    NCBI Gene ID: 142686
    neXtProt AC: NX_A6NK59

  • Chr Location
    3p21.1; chr3:57268351-57292720 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 15445
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ASB14
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    7
  • Gene trapped
    3
  • Targeted
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035287 VEGA Gene Model | MGI Sequence Detail 20702 C57BL/6J ±  kb
transcript OTTMUST00000090164 VEGA | MGI Sequence Detail 2062 Not Applicable  
polypeptide OTTMUSP00000049408 VEGA | MGI Sequence Detail 615 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    144 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000004346 ankyrin repeat and SOCS box protein 14
  • InterPro Domains
    IPR002110 Ankyrin repeat
    IPR020683 Ankyrin repeat-containing domain
    IPR001496 SOCS box domain
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:82306 Kile BT, et al., The SOCS box: a tale of destruction and degradation. Trends Biochem Sci. 2002 May;27(5):235-41
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory