About   Help   FAQ
Sprr4 Gene Detail
Summary
  • Symbol
    Sprr4
  • Name
    small proline-rich protein 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2654508
    NCBI Gene: 229562
Location & Maps
more
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    SPRR4, small proline rich protein 4
  • Human Ortholog
    SPRR4, small proline rich protein 4
    Orthology source: HGNC
  • Links
    NCBI Gene ID: 163778
    neXtProt AC: NX_Q96PI1

  • Chr Location
    1q21.3; chr1:152970653-152972574 (+)  GRCh38.p2

  • HCOP
    human homology predictions: SPRR4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Sprr4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051841 VEGA Gene Model | MGI Sequence Detail 231 C57BL/6J ±  kb
transcript OTTMUST00000130579 VEGA | MGI Sequence Detail 231 Not Applicable  
polypeptide OTTMUSP00000069957 VEGA | MGI Sequence Detail 76 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    19 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015581 small proline-rich protein 4
  • InterPro Domains
    IPR026075 Small proline-rich protein/late cornified envelope protein
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 18
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:81866 Patel S, et al., Mouse Sprr locus: a tandem array of coordinately regulated genes. Mamm Genome. 2003 Feb;14(2):140-8
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory