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Defb8 Gene Detail
Summary
  • Symbol
    Defb8
  • Name
    defensin beta 8
  • Synonyms
    Defr1, mBD8
  • Feature Type
    protein coding gene
  • IDs
    MGI:2654206
    NCBI Gene: 244334
Location & Maps
more
  • Sequence Map
    Chr8:19445769-19447606 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      1838 bp   ±  kb flank

  • Genome Browsers
Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
  • All Mutations and Alleles
    6
  • Gene trapped
    6
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020716 VEGA Gene Model | MGI Sequence Detail 1838 C57BL/6J ±  kb
transcript OTTMUST00000049031 VEGA | MGI Sequence Detail 287 Not Applicable  
polypeptide OTTMUSP00000022638 VEGA | MGI Sequence Detail 60 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    75 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Other 1

    Microarray probesets 2
Other
Accession IDs
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MGI:2179199
References
more
  • Summaries
    All 21
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:78153 Morrison GM, et al., Identification and characterization of a novel murine beta-defensin-related gene. Mamm Genome. 2002 Aug;13(8):445-51
  • Latest
    J:148089 Taylor K, et al., Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6. Eur J Immunol. 2009 May;39(5):1353-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/19/2016
MGI 6.03
The Jackson Laboratory