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Aldh8a1
Gene Detail
Symbol

Name
ID
Aldh8a1
aldehyde dehydrogenase 8 family, member A1
MGI:2653900
Synonyms
RALDH4
Feature Type
protein coding gene
Genetic Map
Chromosome 10
9.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr10:21377291-21396585 bp, + strand
From VEGA annotation of GRCm38

  19295 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23369  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: NAD-dependent aldehyde dehydrogenase
Gene Tree: Aldh8a1

Human
homologs
Human Homolog ALDH8A1, aldehyde dehydrogenase 8 family, member A1
NCBI Gene ID 64577
neXtProt AC  NX_Q9H2A2
Human Synonyms  ALDH12, DJ352A20.2
Human Chr (Location)  6q23.2; chr6:134917390-134950122 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Aldh8a1 interacts with 149 markers (Mir16-1, Mir19b-1, Mir19b-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (7 records)
Data Summary: Results (41)    Tissues (11)    Images (26)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 25
RT-PCR 16
cDNA source data(30)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(32) cDNA(30) Primer pair(1) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000028021 (Evidence)
Ensembl Gene ModelENSMUSG00000037542 (Evidence)
Entrez Gene237320 (Evidence)
UniGene90181
DFCITC1583238
DoTSDT.40138910, DT.97354394, DT.97406297
NIA Mouse Gene IndexU011326
EC1.2.1.-
Consensus CDS ProjectCCDS23723.1
International Mouse Knockout Project StatusAldh8a1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028021 VEGA Gene Model | MGI Sequence Detail 19295 C57BL/6J ±  kb
transcript OTTMUST00000069398 VEGA | MGI Sequence Detail 2259 Not Applicable 
polypeptide OTTMUSP00000035243 VEGA | MGI Sequence Detail 487 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(162 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016160 Aldehyde dehydrogenase, conserved site
InterPro IPR016163 Aldehyde dehydrogenase, C-terminal
InterPro IPR015590 Aldehyde dehydrogenase domain
InterPro IPR016162 Aldehyde dehydrogenase, N-terminal
InterPro IPR016161 Aldehyde/histidinol dehydrogenase
Protein Ontology PR:000003932 aldehyde dehydrogenase family 8 member A1
References
(Earliest) J:83534 Zhuang R, et al., cis-Retinol/androgen dehydrogenase, isozyme 3 (CRAD3): a short-chain dehydrogenase active in a reconstituted path of 9-cis-retinoic acid biosynthesis in intact cells. Biochemistry. 2002 Mar 12;41(10):3477-83
(Latest) J:192460 Ioannou M, et al., ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Dev Biol. 2013 Feb 1;374(1):153-63
All references(39)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory