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Amigo1 Gene Detail
Summary
  • Symbol
    Amigo1
  • Name
    adhesion molecule with Ig like domain 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2653612
    NCBI Gene: 229715
Location & Maps
more
  • Sequence Map
    Chr3:108186350-108192286 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      5937 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 46.86 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    AMIGO1, adhesion molecule with Ig like domain 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    AMIGO1, adhesion molecule with Ig like domain 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ALI2, AMIGO, AMIGO-1
  • Links
    NCBI Gene ID: 57463
    neXtProt AC: NX_Q86WK6

  • Chr Location
    1p13.3; chr1:109504178-109509717 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Amigo1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007182 VEGA Gene Model | MGI Sequence Detail 5937 C57BL/6J ±  kb
transcript OTTMUST00000016567 VEGA | MGI Sequence Detail 5482 Not Applicable  
polypeptide OTTMUSP00000007609 VEGA | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    8 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 4
    Primer pair 1

    Microarray probesets 6
References
more
  • Summaries
    All 28
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:82518 Kuja-Panula J, et al., AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J Cell Biol. 2003 Mar 17;160(6):963-73
  • Latest
    J:229257 Gu Z, et al., Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory