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Mapk15
Gene Detail
Symbol

Name
ID
Mapk15
mitogen-activated protein kinase 15
MGI:2652894
Synonyms
MGC:56865, MGC:56903
Feature Type
protein coding gene
Genetic Map
Chromosome 15
35.20 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:75993769-75999152 bp, + strand
From VEGA annotation of GRCm38

  5384 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:16371  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: MAPK15
Protein SuperFamily: kinase-related transforming protein
Gene Tree: Mapk15

Human
homologs
MAPK15, mitogen-activated protein kinase 15
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 225689
neXtProt AC: NX_Q8TD08

Human Synonyms: ERK7, ERK8

Human Chr (Location): 8q24.3; chr8:143716302-143722463 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Mapk15 (1)
Incidental mutations (data from Mutagenetix , APF )
Phenotype Images(2)
Interactions
Mapk15 interacts with 32 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process MAPK cascade, negative regulation of DNA replication, ...
Component nucleus
Function ATP binding, kinase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (126)    Tissues (18)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 126
cDNA source data(8)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase mapk15 ; ZFIN mapk15    NEW 
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000034960 (Evidence)
Ensembl Gene Model ENSMUSG00000063704 (Evidence)
Entrez Gene 332110 (Evidence)
UniGene 40843
DFCI TC1594496, TC1589198
DoTS DT.97343198, DT.94268323, DT.91415643, DT.99714856
NIA Mouse Gene Index U077215
EC 2.7.11.24
Consensus CDS Project CCDS27558.1
International Mouse Phenotyping Consortium Status Mapk15
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034960 VEGA Gene Model | MGI Sequence Detail 5384 C57BL/6J ±  kb
transcript OTTMUST00000088884 VEGA | MGI Sequence Detail 1929 Not Applicable 
polypeptide OTTMUSP00000048508 VEGA | MGI Sequence Detail 549 Not Applicable 

For the selected sequences
All sequences(52) RefSeq(25) UniProt(2)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003527 Mitogen-activated protein (MAP) kinase, conserved site
InterPro IPR017441 Protein kinase, ATP binding site
InterPro IPR000719 Protein kinase, catalytic domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain
Protein Ontology PR:000010155 mitogen-activated protein kinase 15
References
(Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory