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Cdc42bpg Gene Detail
Summary
  • Symbol
    Cdc42bpg
  • Name
    CDC42 binding protein kinase gamma (DMPK-like)
  • Synonyms
    MRCKgamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:2652845
    NCBI Gene: 240505
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6306457-6325653 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    98 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2652845
protein coding gene Chr19:6306456-6325653 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024758
protein coding gene Chr19:3354260-3373455 (+)
A/J MGP_AJ_G0024724
protein coding gene Chr19:3171076-3190272 (+)
AKR/J MGP_AKRJ_G0024697
protein coding gene Chr19:3264167-3285046 (+)
BALB/cJ MGP_BALBcJ_G0024724
protein coding gene Chr19:3169942-3189436 (+)
C3H/HeJ MGP_C3HHeJ_G0024492
protein coding gene Chr19:3287275-3306471 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025170
protein coding gene Chr19:3409763-3428947 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022604
protein coding gene Chr19:3092903-3113715 (+)
CAST/EiJ MGP_CASTEiJ_G0023964
protein coding gene Chr19:3307178-3327272 (+)
CBA/J MGP_CBAJ_G0024464
protein coding gene Chr19:3580430-3599571 (+)
DBA/2J MGP_DBA2J_G0024591
protein coding gene Chr19:3159863-3178995 (+)
FVB/NJ MGP_FVBNJ_G0024557
protein coding gene Chr19:3174185-3194083 (+)
LP/J MGP_LPJ_G0024677
protein coding gene Chr19:3320820-3340095 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024586
protein coding gene Chr19:3385818-3416314 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025218
protein coding gene Chr19:3293362-3312772 (+)
PWK/PhJ MGP_PWKPhJ_G0023710
protein coding gene Chr19:3189796-3209198 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023515
protein coding gene Chr19:3252398-3271585 (+)
WSB/EiJ MGP_WSBEiJ_G0024026
protein coding gene Chr19:3305824-3325945 (+)



Homology
more
  • Human Ortholog
    CDC42BPG, CDC42 binding protein kinase gamma
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CDC42BPG, CDC42 binding protein kinase gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DMPK2, HSMDPKIN, KAPPA-200, MRCKG, MRCKgamma
  • Links
    NCBI Gene ID: 55561
    neXtProt AC: NX_Q6DT37
    UniProt: Q6DT37

  • Chr Location
    11q13.1; chr11:64823809-64844685 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 240505 NCBI Gene Model | MGI Sequence Detail 19197 C57BL/6J ±  kb
transcript NM_001033342 RefSeq | MGI Sequence Detail 5994 C57BL/6  
polypeptide Q80UW5 UniProt | EBI | MGI Sequence Detail 1551 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    Genomic 1
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:239907 Fulcoli FG, et al., Rebalancing gene haploinsufficiency in vivo by targeting chromatin. Nat Commun. 2016 Jun 03;7:11688

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory