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Dcdc2a
Gene Detail
 Symbol
Name
ID
Dcdc2a
doublecortin domain containing 2a
MGI:2652818
Synonyms Dcdc2, MGC:54817, RU2
Feature Type protein coding gene
Genetic Map
Chromosome 13
10.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr13:25056004-25210706 bp, + strand
From VEGA annotation of GRCm38

  154703 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9483  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dcdc2a

Human
homologs
Human Homolog DCDC2, doublecortin domain containing 2
NCBI Gene ID 51473
neXtProt AC  NX_Q9UHG0
Human Synonyms  DCDC2A, RU2, RU2S
Human Chr (Location)  6p22.1; chr6:24171755-24383292 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit impaired short term object recognition, impaired visuo-spatial learning and memory adn increased anxiety-related response.
 
Interactions
Dcdc2a interacts with 419 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process dendrite morphogenesis, intracellular signal transduction, ...
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (90)    Tissues (28)    Images (22)
Theiler Stages: 22, 23, 26, 28
Assay TypeResults
RNA in situ 90
cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) cDNA(13) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000000615 (Evidence)
Ensembl Gene ModelENSMUSG00000035910 (Evidence)
Entrez Gene195208 (Evidence)
UniGene284719
DFCITC1588866, TC1592162, TC1598797, TC1724928
DoTSDT.101253488, DT.101335921, DT.55231518, DT.97387406
NIA Mouse Gene IndexU014670, U306834, U371284
Consensus CDS ProjectCCDS26386.2, CCDS56873.1
International Mouse Knockout Project StatusDcdc2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000000615 VEGA Gene Model | MGI Sequence Detail 154703 C57BL/6J ±  kb
transcript OTTMUST00000001217 VEGA | MGI Sequence Detail 6634 Not Applicable 
polypeptide OTTMUSP00000000572 VEGA | MGI Sequence Detail 475 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(18) UniProt(2)
Polymorphisms SNPs within 2kb(1683 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1685)
Protein-related
information
ResourceIDDescription
InterPro IPR003533 Doublecortin domain
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:191236 Wang SZ, et al., Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18589-94
All references(34)
Other
accession IDs
MGI:2145433

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory