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Il1f10 Gene Detail
Summary
  • Symbol
    Il1f10
  • Name
    interleukin 1 family, member 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2652548
    NCBI Gene: 215274
  • Gene Overview
    MyGene.info: IL1F10
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr2:24291196-24293820 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 16.32 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    94 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2652548
protein coding gene Chr2:24291196-24293820 (.)
129S1/SvImJ MGP_129S1SvImJ_G0025407
protein coding gene Chr2:22085755-22088391 (+)
A/J MGP_AJ_G0025384
protein coding gene Chr2:21236686-21239309 (+)
AKR/J MGP_AKRJ_G0025354
protein coding gene Chr2:21965492-21968115 (+)
BALB/cJ MGP_BALBcJ_G0025380
protein coding gene Chr2:21347097-21349721 (+)
C3H/HeJ MGP_C3HHeJ_G0025141
protein coding gene Chr2:21903745-21906369 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025824
protein coding gene Chr2:22796158-22798782 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023235
protein coding gene Chr2:20163536-20166727 (+)
CAST/EiJ MGP_CASTEiJ_G0024604
protein coding gene Chr2:21734784-21737484 (+)
CBA/J MGP_CBAJ_G0025119
protein coding gene Chr2:23600954-23603651 (+)
DBA/2J MGP_DBA2J_G0025252
protein coding gene Chr2:21095677-21098316 (+)
FVB/NJ MGP_FVBNJ_G0025214
protein coding gene Chr2:20837350-20839965 (+)
LP/J MGP_LPJ_G0025338
protein coding gene Chr2:22016917-22019574 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025245
protein coding gene Chr2:23839314-23841938 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025883
protein coding gene Chr2:21888332-21890956 (+)
PWK/PhJ MGP_PWKPhJ_G0024352
protein coding gene Chr2:20880454-20883093 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024152
protein coding gene Chr2:22004503-22007122 (+)
WSB/EiJ MGP_WSBEiJ_G0024673
protein coding gene Chr2:21961781-21964429 (+)



Homology
more
  • Human Ortholog
    IL1F10, interleukin 1 family member 10
  • Vertebrate Orthologs
    6
  • Human Ortholog
    IL1F10, interleukin 1 family member 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FIL1-theta, FKSG75, IL1HY2, IL-1HY2, IL1-theta, IL-38
  • Links
    NCBI Gene ID: 84639
    neXtProt AC: NX_Q8WWZ1
    UniProt: Q8WWZ1

  • Chr Location
    2q14.1; chr2:113067970-113075850 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 215274 NCBI Gene Model | MGI Sequence Detail 2625 C57BL/6J ±  kb
transcript NM_153077 RefSeq | MGI Sequence Detail 538 C57BL/6  
polypeptide Q8R459 UniProt | EBI | MGI Sequence Detail 152 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
References
more
  • Summaries
    All 25
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:76507 Taylor SL, et al., Genomic organization of the interleukin-1 locus. Genomics. 2002 May;79(5):726-33
  • Latest
    J:260118 Palomo J, et al., The severity of imiquimod-induced mouse skin inflammation is independent of endogenous IL-38 expression. PLoS One. 2018;13(3):e0194667

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory