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Klhdc3 Gene Detail
Summary
  • Symbol
    Klhdc3
  • Name
    kelch domain containing 3
  • Synonyms
    1300011D16Rik, Peas
  • Feature Type
    protein coding gene
  • IDs
    MGI:2651568
    NCBI Gene: 71765
  • Gene Overview
    MyGene.info: KLHDC3
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:46674550-46680930 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 22.90 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    40 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2651568
protein coding gene Chr17:46674550-46680930 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023826
protein coding gene Chr17:47754759-47761132 (-)
A/J MGP_AJ_G0023784
protein coding gene Chr17:46607036-46613420 (-)
AKR/J MGP_AKRJ_G0023755
protein coding gene Chr17:46952203-46958575 (-)
BALB/cJ MGP_BALBcJ_G0023788
protein coding gene Chr17:46507435-46513856 (-)
C3H/HeJ MGP_C3HHeJ_G0023551
protein coding gene Chr17:47698289-47704678 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024231
protein coding gene Chr17:49804030-49810430 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021681
protein coding gene Chr17:43388641-43395141 (-)
CAST/EiJ MGP_CASTEiJ_G0023033
protein coding gene Chr17:47781982-47788352 (-)
CBA/J MGP_CBAJ_G0023528
protein coding gene Chr17:51597352-51603740 (-)
DBA/2J MGP_DBA2J_G0023654
protein coding gene Chr17:45377525-45383918 (-)
FVB/NJ MGP_FVBNJ_G0023621
protein coding gene Chr17:45000511-45006935 (-)
LP/J MGP_LPJ_G0023735
protein coding gene Chr17:48433676-48440112 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023650
protein coding gene Chr17:51142088-51148466 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024276
protein coding gene Chr17:47305831-47312236 (-)
PWK/PhJ MGP_PWKPhJ_G0022778
protein coding gene Chr17:44717773-44724333 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022593
protein coding gene Chr17:44175686-44182052 (-)
WSB/EiJ MGP_WSBEiJ_G0023098
protein coding gene Chr17:47859520-47865893 (-)



Homology
more
  • Human Ortholog
    KLHDC3, kelch domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    KLHDC3, kelch domain containing 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    dJ20C7.3, PEAS
  • Links
    NCBI Gene ID: 116138
    neXtProt AC: NX_Q9BQ90
    UniProt: Q9BQ90

  • Chr Location
    6p21.1; chr6:43014103-43021298 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14290
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KLHDC3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71765 NCBI Gene Model | MGI Sequence Detail 6381 C57BL/6J ±  kb
transcript NM_027910 RefSeq | MGI Sequence Detail 2139 C57BL/6  
polypeptide Q8VEM9 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR011498 Kelch repeat type 2
    IPR015915 Kelch-type beta propeller
Molecular
Reagents
less
  • All nucleic 199
    cDNA 199

    Microarray probesets 4
Other
Accession IDs
less
MGI:1919015
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory