About   Help   FAQ
Adgrb2 Gene Detail
Summary
  • Symbol
    Adgrb2
  • Name
    adhesion G protein-coupled receptor B2
  • Synonyms
    Bai2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2451244
    NCBI Gene: 230775
Location & Maps
more
  • Sequence Map
    Chr4:129984870-130022633 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      37764 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.43 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    ADGRB2, adhesion G protein-coupled receptor B2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADGRB2, adhesion G protein-coupled receptor B2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BAI2
  • Links
    NCBI Gene ID: 576
    neXtProt AC: NX_O60241
    UniProt: O60241

  • Chr Location
    1p35.2; chr1:31727105-31764063 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 3 alleles in 3 genetic backgrounds
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene show a lessening of depression like behavior.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009519 VEGA Gene Model | MGI Sequence Detail 37764 C57BL/6J ±  kb
transcript OTTMUST00000090352 VEGA | MGI Sequence Detail 4734 Not Applicable  
polypeptide OTTMUSP00000049547 VEGA | MGI Sequence Detail 1577 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    262 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    cDNA 56
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:23094 Davisson MT, New chromosome aberrations. Mouse News Lett. 1988;80:166
  • Latest
    J:219706 Kakegawa W, et al., Anterograde C1ql1 signaling is required in order to determine and maintain a single-winner climbing fiber in the mouse cerebellum. Neuron. 2015 Jan 21;85(2):316-29

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/16/2017
MGI 6.09
The Jackson Laboratory