Xylt1
Gene Detail

Symbol Name ID

Xylt1 xylosyltransferase 1 MGI:2451073

Feature Type

protein coding gene

Genetic Map

Chromosome 7

62.93 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)

Sequence Map

Chr7:117380979-117667751 bp, + strand From VEGA annotation of GRCm38   286773 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32534  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Xylt1

Human homologs

Human Homolog		XYLT1, xylosyltransferase I
NCBI Gene ID		64131
neXtProt AC		NX_Q86Y38
Human Synonyms		PXYLT1, XT1, XTI, XT-I, XYLTI
Human Chr (Location)		16p12.3; chr16:17196181-17564738 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human XYLT1

Alleles and phenotypes

All alleles(2) : Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	cellular response to heat, glycosaminoglycan biosynthetic process, ...
Component	endoplasmic reticulum, Golgi apparatus, ...
Function	acetylglucosaminyltransferase activity, protein xylosyltransferase activity, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (26)    Tissues (2)    Images (2)
Theiler Stages: 26, 28

Assay Type	Results
RT-PCR	26

cDNA source data(2)
External Resources: GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(2) Primer pair(1) Other(1)
Microarray probesets(1)

Other database links

VEGA Gene Model	OTTMUSG00000032722 (Evidence)
Ensembl Gene Model	ENSMUSG00000030657 (Evidence)
Entrez Gene	233781 (Evidence)
UniGene	461427
DFCI	TC1589153, TC1629763
DoTS	DT.101275505, DT.101300429, DT.91294456
NIA Mouse Gene Index	U008673
EC	2.4.2.26
Consensus CDS Project	CCDS40101.1
International Mouse Knockout Project Status	Xylt1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000032722	VEGA Gene Model | MGI Sequence Detail	286773	C57BL/6J
transcript	OTTMUST00000081402	VEGA | MGI Sequence Detail	3191	Not Applicable
polypeptide	OTTMUSP00000043549	VEGA | MGI Sequence Detail	953	Not Applicable

All sequences(29) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(1701 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR003406	Glycosyl transferase, family 14
InterPro	IPR024448	Xylosyltransferase
Protein Ontology	PR:000017515	xylosyltransferase 1

References

(Earliest) J:66285 Gotting C, et al., Molecular cloning and expression of human UDP-d-Xylose:Proteoglycan core protein beta-d-xylosyltransferase and its first isoform XT-II. J Mol Biol. 2000 Dec 8;304(4):517-28
(Latest) J:142548 Fujimoto M, et al., Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses. J Biol Chem. 2008 Oct 31;283(44):29961-70
All references(25)