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Pilrb1
Gene Detail
Symbol

Name
ID
Pilrb1
paired immunoglobin-like type 2 receptor beta 1
MGI:2450532
Synonyms
Fdact, Pilrb
Feature Type
protein coding gene
Genetic Map
Chromosome 5
76.82 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr5:137852147-137858106 bp, - strand
From VEGA annotation of GRCm38

  5960 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:114502  Vertebrate Homology Class
1 human; 2 mouse; 18 rat; 1 chimpanzee; 1 rhesus macaque

HCOP human homology predictions: PILRB
Gene Tree: Pilrb1

Human
homologs
PILRB, paired immunoglobin-like type 2 receptor beta
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 29990
neXtProt AC: NX_Q9UKJ0

Human Synonyms: FDFACT1, FDFACT2

Human Chr (Location): 7q22.1; chr7:100358003-100367831 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit decreased susceptiblity to bacterial infection with S. aureus with decreased worm burden and mortality.
 
Interactions
Pilrb1 interacts with 39 markers (Mir23a, Mir27a, Mir27b, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(4)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(4) cDNA(4)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000054648 (Evidence)
Ensembl Gene Model ENSMUSG00000066684 (Evidence)
Entrez Gene 170741 (Evidence)
UniGene 347593
DoTS DT.101376067
Consensus CDS Project CCDS51675.1
International Mouse Phenotyping Consortium Status Pilrb1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000054648 VEGA Gene Model | MGI Sequence Detail 5960 C57BL/6J ±  kb
transcript OTTMUST00000135490 VEGA | MGI Sequence Detail 1807 Not Applicable 
polypeptide OTTMUSP00000071692 VEGA | MGI Sequence Detail 225 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(10) UniProt(5)
Polymorphisms
SNPs within 2kb(19 from dbSNP Build 137)    SNPs within 2kb including multiple locations(45)
Protein-related
information
ResourceIDDescription
InterPro IPR013783 Immunoglobulin-like fold
Protein Ontology PR:000012731 paired immunoglobulin-like type 2 receptor beta
References
(Earliest) J:77738 Fournier N, et al., FDF03, a novel inhibitory receptor of the immunoglobulin superfamily, is expressed by human dendritic and myeloid cells. J Immunol. 2000 Aug 1;165(3):1197-209
(Latest) J:187128 Tato CM, et al., The myeloid receptor PILRbeta mediates the balance of inflammatory responses through regulation of IL-27 production. PLoS One. 2012;7(3):e31680
All references(23)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory