About   Help   FAQ
Arhgap32
Gene Detail
Symbol

Name
ID
Arhgap32
Rho GTPase activating protein 32
MGI:2450166
Synonyms
3426406O18Rik, GC-GAP, Grit, p200RhoGAP, PX-RICS
Feature Type
protein coding gene
Genetic Map
Chromosome 9
17.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr9:32116136-32268446 bp, + strand
From VEGA annotation of GRCm38

  152311 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:8812  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: ARHGAP32
Gene Tree: Arhgap32

Human
homologs
ARHGAP32, Rho GTPase activating protein 32
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 9743
neXtProt AC: NX_A7KAX9

Human Synonyms: GC-GAP, GRIT, p200RhoGAP, p250GAP, PX-RICS, RICS

Human Chr (Location): 11q24.3; chr11:128965060-129267015 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(112) : Gene trapped(111) Targeted(1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a null mutation are fertile but display abnormal neurite growth.
 
Interactions
Arhgap32 interacts with 527 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (59)    Tissues (18)    Images (3)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 3
Northern blot 8
Western blot 48
cDNA source data(34)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase arhgap32 ; ZFIN arhgap32b    NEW 
Molecular
reagents
All nucleic(34) cDNA(34)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000036900 (Evidence)
Ensembl Gene Model ENSMUSG00000041444 (Evidence)
Entrez Gene 330914 (Evidence)
UniGene 46683
DFCI TC1658394, TC1719797, TC1696156, TC1583103
DoTS DT.94301329, DT.101314695, DT.101707001, DT.60104895, DT.87032784
NIA Mouse Gene Index U286895, U010225, U010223
Consensus CDS Project CCDS22951.3, CCDS57666.1
International Mouse Phenotyping Consortium Status Arhgap32
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000036900 VEGA Gene Model | MGI Sequence Detail 152311 C57BL/6J ±  kb
transcript OTTMUST00000094795 VEGA | MGI Sequence Detail 13568 Not Applicable 
polypeptide OTTMUSP00000052829 VEGA | MGI Sequence Detail 2089 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(11) UniProt(5)
Polymorphisms
SNPs within 2kb(638 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR000198 Rho GTPase-activating protein domain
InterPro IPR008936 Rho GTPase activation protein
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000013998 rho/Cdc42/Rac GTPase-activating protein RICS
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:205566 Marler KJ, et al., BDNF Promotes Axon Branching of Retinal Ganglion Cells via miRNA-132 and p250GAP. J Neurosci. 2014 Jan 15;34(3):969-79
All references(41)
Other
accession IDs
MGI:1917927

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory