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Cog3 Gene Detail
Summary
  • Symbol
    Cog3
  • Name
    component of oligomeric golgi complex 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2450151
    NCBI Gene: 338337
  • Gene Overview
    MyGene.info: COG3
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:75702350-75754517 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 40.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    306 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2450151
protein coding gene Chr14:75702350-75754576 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021573
protein coding gene Chr14:70558726-70610833 (-)
A/J MGP_AJ_G0021531
protein coding gene Chr14:68961931-69014816 (-)
AKR/J MGP_AKRJ_G0021508
protein coding gene Chr14:71017618-71070059 (-)
BALB/cJ MGP_BALBcJ_G0021538
protein coding gene Chr14:68758712-68812436 (-)
C3H/HeJ MGP_C3HHeJ_G0021315
protein coding gene Chr14:70742822-70795126 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021978
protein coding gene Chr14:73642165-73694015 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019516
protein coding gene Chr14:66583261-66636159 (-)
CAST/EiJ MGP_CASTEiJ_G0020832
protein coding gene Chr14:67408270-67462307 (-)
CBA/J MGP_CBAJ_G0021283
protein coding gene Chr14:75995821-76055219 (-)
DBA/2J MGP_DBA2J_G0021406
protein coding gene Chr14:68370536-68422760 (-)
FVB/NJ MGP_FVBNJ_G0021384
protein coding gene Chr14:67703997-67756097 (-)
LP/J MGP_LPJ_G0021476
protein coding gene Chr14:71720503-71774402 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021411
protein coding gene Chr14:74743307-74798530 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022001
protein coding gene Chr14:70287315-70339269 (-)
PWK/PhJ MGP_PWKPhJ_G0020575
protein coding gene Chr14:65107811-65160948 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020412
protein coding gene Chr14:66262745-66320188 (-)
WSB/EiJ MGP_WSBEiJ_G0020885
protein coding gene Chr14:70631809-70688091 (-)



Homology
more
  • Human Ortholog
    COG3, component of oligomeric golgi complex 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COG3, component of oligomeric golgi complex 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SEC34
  • Links
    NCBI Gene ID: 83548
    neXtProt AC: NX_Q96JB2
    UniProt: Q96JB2

  • Chr Location
    13q14.13; chr13:45464895-45536698 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5854
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COG3
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034893 Ensembl Gene Model | MGI Sequence Detail 52168 C57BL/6J ±  kb
    transcript ENSMUST00000049168 Ensembl | MGI Sequence Detail 4222 Not Applicable  
    polypeptide ENSMUSP00000045016 Ensembl | MGI Sequence Detail 828 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR007265 Conserved oligomeric Golgi complex, subunit 3
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 3
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory