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Noxa1 Gene Detail
Summary
  • Symbol
    Noxa1
  • Name
    NADPH oxidase activator 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449980
    NCBI Gene: 241275
  • Gene Overview
    MyGene.info: NOXA1
Location & Maps
more
  • Sequence Map
    Chr2:25085667-25095149 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      9483 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NOXA1, NADPH oxidase activator 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NOXA1, NADPH oxidase activator 1
    Orthology source: HomoloGene
  • Synonyms
    NY-CO-31, p51NOX, SDCCAG31
  • Links
    NCBI Gene ID: 10811
    neXtProt AC: NX_Q86UR1

  • Chr Location
    9q34.3; chr9:137423395-137434406 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    1 phenotype reference
Mice homozygous for a targeted allele removing exons 3 through 6 exhibit no overt phenotypic abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011780 VEGA Gene Model | MGI Sequence Detail 9483 C57BL/6J ±  kb
transcript OTTMUST00000027646 VEGA | MGI Sequence Detail 1617 Not Applicable  
polypeptide OTTMUSP00000012559 VEGA | MGI Sequence Detail 444 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    94 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 1
  • Earliest
    J:81679 Banfi B, et al., Two novel proteins activate superoxide generation by the NADPH oxidase NOX1. J Biol Chem. 2003 Feb 7;278(6):3510-3
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory