Il1f9 Gene Detail

Summary

• Symbol
  Il1f9
• Name
  interleukin 1 family, member 9

• Feature Type
  protein coding gene
• IDs
  MGI:2449929
  NCBI Gene: 215257
• Gene Overview
  MyGene.info: IL36G
• Alliance
  gene page
• Transcription Start Sites
  7 TSS

Location &
Maps

• Sequence Map
  Chr2:24186476-24193567 bp, + strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 16.24 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  28 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2449929	protein coding gene	Chr2:24186476-24193568 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025404	protein coding gene	Chr2:21969667-21978019 (+)
A/J	MGP_AJ_G0025381	protein coding gene	Chr2:21130783-21137495 (+)
AKR/J	MGP_AKRJ_G0025350	protein coding gene	Chr2:21833905-21857087 (+)
BALB/cJ	MGP_BALBcJ_G0025376	protein coding gene	Chr2:21239941-21247612 (+)
C3H/HeJ	MGP_C3HHeJ_G0025137	protein coding gene	Chr2:21791951-21802556 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025821	protein coding gene	Chr2:22664186-22675734 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023232	protein coding gene	Chr2:20082497-20091924 (+)
CAST/EiJ	MGP_CASTEiJ_G0024602	protein coding gene	Chr2:21660130-21668749 (-)
CBA/J	MGP_CBAJ_G0025115	protein coding gene	Chr2:23494538-23502878 (+)
DBA/2J	MGP_DBA2J_G0025249	protein coding gene	Chr2:20996188-21003789 (+)
FVB/NJ	MGP_FVBNJ_G0025211	protein coding gene	Chr2:20727397-20734952 (+)
LP/J	MGP_LPJ_G0025334	protein coding gene	Chr2:21906845-21913657 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025242	protein coding gene	Chr2:23706490-23723935 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025880	protein coding gene	Chr2:21767580-21775535 (+)
PWK/PhJ	MGP_PWKPhJ_G0024349	protein coding gene	Chr2:20781159-20788613 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024149	protein coding gene	Chr2:21892662-21899234 (+)
WSB/EiJ	MGP_WSBEiJ_G0024670	protein coding gene	Chr2:21861547-21869665 (+)

Homology

• Human Ortholog
  IL36G, interleukin 36 gamma

• Vertebrate Orthologs
  7

• Human Ortholog
  IL36G, interleukin 36 gamma
  Orthology source: HomoloGene, HGNC
• Synonyms
  IL1E, IL1F9, IL-1F9, IL1H1, IL-1H1, IL1RP2, IL-1RP2
• Links
  HGNC:15741

  NCBI Gene ID: 56300

  neXtProt AC: NX_Q9NZH8

  UniProt: Q9NZH8

  
  
• Chr Location
  2q14.1; chr2:112978019-112985672 (+)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 49595
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 macaque, rhesus
  
• HCOP
  human homology predictions: IL36G
• Gene Tree
  Il1f9
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  3
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  22
• GO References
  5

• External Resources
  FuncBase

Expression

• cDNA Data
  8
• Literature Summary
  2

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Interactions

• Il1f9 interacts with 149 markers (Mir7-1, Mir15a, Mir15b, ...) View All

Sequences &
Gene Models

• All Sequences
  32
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS50518.1
• UniGene
  249379

• Ensembl
  ENSMUSG00000044103 (Evidence)
• NCBI Gene
  215257

Representative Sequences			Length	Strain/Species
genomic	215257	NCBI Gene Model | MGI Sequence Detail	7092	C57BL/6J
transcript	NM_153511	RefSeq | MGI Sequence Detail	1647	C57BL/6
polypeptide	Q8R460	UniProt | EBI | MGI Sequence Detail	164	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR008996 Cytokine IL1/FGF
  IPR000975 Interleukin-1 family

Molecular
Reagents

• All nucleic 8

  cDNA 8

  
  

  Microarray probesets 2

References

• Summaries
  All 33

  Developmental Gene Expression 2

  Gene Ontology 5

  Phenotypes 9
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:266673 Muller A, et al., IkappaBzeta is a key transcriptional regulator of IL-36-driven psoriasis-related gene expression in keratinocytes. Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10088-10093

TSS for Il1f9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr16555	Chr2:24186313-24186322 (+)	-158 bp
Tssr16556	Chr2:24186393-24186402 (+)	-78 bp
Tssr16557	Chr2:24186435-24186451 (+)	-33 bp
Tssr16558	Chr2:24186453-24186464 (+)	-17 bp
Tssr16559	Chr2:24186469-24186484 (+)	1 bp
Tssr16560	Chr2:24186505-24186512 (+)	33 bp
Tssr16561	Chr2:24186770-24186793 (+)	306 bp