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Il1f9 Gene Detail
Summary
  • Symbol
    Il1f9
  • Name
    interleukin 1 family, member 9
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449929
    NCBI Gene: 215257
  • Gene Overview
    MyGene.info: IL36G
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:24186476-24193567 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 16.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    28 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2449929
 protein coding gene Chr2:24186476-24193568 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025404
 protein coding gene Chr2:21969667-21978019 (+)
A/J MGP_AJ_G0025381
 protein coding gene Chr2:21130783-21137495 (+)
AKR/J MGP_AKRJ_G0025350
 protein coding gene Chr2:21833905-21857087 (+)
BALB/cJ MGP_BALBcJ_G0025376
 protein coding gene Chr2:21239941-21247612 (+)
C3H/HeJ MGP_C3HHeJ_G0025137
 protein coding gene Chr2:21791951-21802556 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025821
 protein coding gene Chr2:22664186-22675734 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023232
 protein coding gene Chr2:20082497-20091924 (+)
CAST/EiJ MGP_CASTEiJ_G0024602
 protein coding gene Chr2:21660130-21668749 (-)
CBA/J MGP_CBAJ_G0025115
 protein coding gene Chr2:23494538-23502878 (+)
DBA/2J MGP_DBA2J_G0025249
 protein coding gene Chr2:20996188-21003789 (+)
FVB/NJ MGP_FVBNJ_G0025211
 protein coding gene Chr2:20727397-20734952 (+)
LP/J MGP_LPJ_G0025334
 protein coding gene Chr2:21906845-21913657 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025242
 protein coding gene Chr2:23706490-23723935 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025880
 protein coding gene Chr2:21767580-21775535 (+)
PWK/PhJ MGP_PWKPhJ_G0024349
 protein coding gene Chr2:20781159-20788613 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024149
 protein coding gene Chr2:21892662-21899234 (+)
WSB/EiJ MGP_WSBEiJ_G0024670
 protein coding gene Chr2:21861547-21869665 (+)



Homology
more
  • Human Ortholog
    IL36G, interleukin 36 gamma
  • Vertebrate Orthologs
    7
  • Human Ortholog
    IL36G, interleukin 36 gamma
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IL1E, IL1F9, IL-1F9, IL1H1, IL-1H1, IL1RP2, IL-1RP2
  • Links
    NCBI Gene ID: 56300
    neXtProt AC: NX_Q9NZH8
    UniProt: Q9NZH8

  • Chr Location
    2q14.1; chr2:112978019-112985672 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • cDNA Data
    8
  • Literature Summary
    2
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 215257 NCBI Gene Model | MGI Sequence Detail 7092 C57BL/6J ±  kb
transcript NM_153511 RefSeq | MGI Sequence Detail 1647 C57BL/6  
polypeptide Q8R460 UniProt | EBI | MGI Sequence Detail 164 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR008996 Cytokine IL1/FGF
    IPR000975 Interleukin-1 family
Molecular
Reagents
less
  • All nucleic 8
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:280917 Gardner JK, et al., IL-36gamma Is a Key Regulator of Neutrophil Infiltration in the Vaginal Microenvironment and Limits Neuroinvasion in Genital HSV-2 Infection. J Immunol. 2019 Nov 15;203(10):2655-2664
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2020
MGI 6.15 		The Jackson Laboratory