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Alpk2 Gene Detail
Summary
  • Symbol
    Alpk2
  • Name
    alpha-kinase 2
  • Synonyms
    Hak
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449492
    NCBI Gene: 225638
  • Alliance
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:65265529-65393888 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 38.41 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1187 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2449492
protein coding gene Chr18:65265529-65393888 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024507
protein coding gene Chr18:65386579-65531568 (-)
A/J MGP_AJ_G0024474
protein coding gene Chr18:62561051-62689136 (-)
AKR/J MGP_AKRJ_G0024444
protein coding gene Chr18:64318832-64459593 (-)
BALB/cJ MGP_BALBcJ_G0024473
protein coding gene Chr18:62698491-62828301 (-)
C3H/HeJ MGP_C3HHeJ_G0024241
protein coding gene Chr18:64523088-64653706 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024920
protein coding gene Chr18:67149033-67283049 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022351
protein coding gene Chr18:62003132-62126695 (-)
CAST/EiJ MGP_CASTEiJ_G0023714
protein coding gene Chr18:64482416-64629623 (-)
CBA/J MGP_CBAJ_G0024211
protein coding gene Chr18:69320617-69476935 (-)
DBA/2J MGP_DBA2J_G0024341
protein coding gene Chr18:62213932-62342255 (-)
FVB/NJ MGP_FVBNJ_G0024307
protein coding gene Chr18:61605047-61738282 (-)
LP/J MGP_LPJ_G0024425
protein coding gene Chr18:65249150-65386780 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024336
protein coding gene Chr18:70776402-70910386 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024967
protein coding gene Chr18:64542063-64667885 (-)
PWK/PhJ MGP_PWKPhJ_G0023457
protein coding gene Chr18:62469815-62597993 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023262
protein coding gene Chr18:64682285-64820073 (-)
WSB/EiJ MGP_WSBEiJ_G0023778
protein coding gene Chr18:64392852-64521336 (-)



Homology
more
  • Human Ortholog
    ALPK2, alpha kinase 2
  • Vertebrate Orthologs
    6
  • Human Ortholog
    ALPK2, alpha kinase 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HAK
  • Links
    NCBI Gene ID: 115701
    neXtProt AC: NX_Q86TB3
    UniProt: Q86TB3

  • Chr Location
    18q21.31-q21.32; chr18:58481247-58629192 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225638 NCBI Gene Model | MGI Sequence Detail 128360 C57BL/6J ±  kb
transcript NM_001037294 RefSeq | MGI Sequence Detail 7250 C57BL/6  
polypeptide Q91ZB0 UniProt | EBI | MGI Sequence Detail 2144 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:78800 Ryazanov AG, et al., Alpha-kinases: a new class of protein kinases with a novel catalytic domain. Curr Biol. 1999 Jan 28;9(2):R43-5
  • Latest
    J:188254 Budry L, et al., The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory