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Adamts10 Gene Detail
Summary
  • Symbol
    Adamts10
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
  • Synonyms
    ZnMP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449112
    NCBI Gene: 224697
  • Gene Overview
    MyGene.info: ADAMTS10
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:33524204-33553782 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    291 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2449112
protein coding gene Chr17:33524121-33553782 (.)
129S1/SvImJ MGP_129S1SvImJ_G0023529
protein coding gene Chr17:33442356-33472583 (+)
A/J MGP_AJ_G0023488
protein coding gene Chr17:32298359-32329009 (+)
AKR/J MGP_AKRJ_G0023454
protein coding gene Chr17:32674526-32704896 (+)
BALB/cJ MGP_BALBcJ_G0023492
protein coding gene Chr17:32445663-32475268 (+)
C3H/HeJ MGP_C3HHeJ_G0023255
protein coding gene Chr17:33011336-33041586 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023936
protein coding gene Chr17:34668814-34698392 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021409
protein coding gene Chr17:29829498-29859564 (+)
CAST/EiJ MGP_CASTEiJ_G0022757
protein coding gene Chr17:33130815-33161398 (+)
CBA/J MGP_CBAJ_G0023231
protein coding gene Chr17:36073347-36106308 (+)
DBA/2J MGP_DBA2J_G0023360
protein coding gene Chr17:31689623-31719788 (+)
FVB/NJ MGP_FVBNJ_G0023329
protein coding gene Chr17:31529294-31559697 (+)
LP/J MGP_LPJ_G0023438
protein coding gene Chr17:33728046-33757654 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023349
protein coding gene Chr17:35141401-35171949 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023976
protein coding gene Chr17:33001024-33030632 (+)
PWK/PhJ MGP_PWKPhJ_G0022505
protein coding gene Chr17:30580882-30611185 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022321
protein coding gene Chr17:30972769-31002696 (+)
WSB/EiJ MGP_WSBEiJ_G0022816
protein coding gene Chr17:33046588-33077742 (+)



Homology
more
  • Human Ortholog
    ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ADAM-TS10, ADAMTS-10, WMS, WMS1
  • Links
    NCBI Gene ID: 81794
    neXtProt AC: NX_Q9H324
    UniProt: Q9H324

  • Chr Location
    19p13.2; chr19:8580240-8610735 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ADAMTS10 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024299 Ensembl Gene Model | MGI Sequence Detail 29579 C57BL/6J ±  kb
transcript ENSMUST00000087623 Ensembl | MGI Sequence Detail 4043 Not Applicable  
polypeptide ENSMUSP00000084905 Ensembl | MGI Sequence Detail 1104 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 65
    Genomic 2
    cDNA 61
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147031
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80645 Carninci P, et al., High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44
  • Latest
    J:266167 Matsuzaki T, et al., The RECK tumor-suppressor protein binds and stabilizes ADAMTS10. Biol Open. 2018 Oct 4;7(10)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory