About   Help   FAQ
Adamts10 Gene Detail
Summary
  • Symbol
    Adamts10
  • Name
    a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
  • Synonyms
    ZnMP
  • Feature Type
    protein coding gene
  • IDs
    MGI:2449112
    NCBI Gene: 224697
  • Gene Overview
    MyGene.info: ADAMTS10
Location & Maps
more
  • Sequence Map
    Chr17:33524204-33553782 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      29579 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.98 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif 10
    Orthology source: HomoloGene
  • Synonyms
    ADAM-TS10, ADAMTS-10, WMS, WMS1
  • Links
    NCBI Gene ID: 81794
    neXtProt AC: NX_Q9H324

  • Chr Location
    19p13.2; chr19:8580240-8610753 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human ADAMTS10 associations

Human Disease Mouse Models
       Weill-Marchesani Syndrome 1; WMS1   OMIM: 277600
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037200 VEGA Gene Model | MGI Sequence Detail 29579 C57BL/6J ±  kb
transcript OTTMUST00000095898 VEGA | MGI Sequence Detail 4043 Not Applicable  
polypeptide OTTMUSP00000053537 VEGA | MGI Sequence Detail 1104 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    291 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    Genomic 1
    cDNA 60
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2147031
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:80645 Carninci P, et al., High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44
  • Latest
    J:224408 Dubail J, et al., Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics. Matrix Biol. 2015 May-Jul;44-46:24-37

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/22/2016
MGI 6.04
The Jackson Laboratory