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Adamts10
Gene Detail
Symbol

Name
ID
Adamts10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
MGI:2449112
Synonyms
ZnMP
Feature Type
protein coding gene
Genetic Map
Chromosome 17
17.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:33524204-33553782 bp, + strand
From VEGA annotation of GRCm38

  29579 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:81940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Adamts10

Human
homologs
Human Homolog ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif, 10
NCBI Gene ID 81794
neXtProt AC  NX_Q9H324
Human Synonyms  ADAM-TS10, ADAMTS-10, WMS, WMS1
Human Chr (Location)  19p13.2; chr19:8580240-8610753 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ADAMTS10
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adamts10 interacts with 322 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process proteolysis
Component extracellular matrix, extracellular region, ...
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (10)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 10
cDNA source data(60)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(63) Genomic(1) cDNA(60) Primer pair(2)
Microarray probesets(5)
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037200 VEGA Gene Model | MGI Sequence Detail 29579 C57BL/6J ±  kb
transcript OTTMUST00000095898 VEGA | MGI Sequence Detail 4043 Not Applicable 
polypeptide OTTMUSP00000053537 VEGA | MGI Sequence Detail 1104 Not Applicable 

For the selected sequences
All sequences(115) RefSeq(18) UniProt(7)
Polymorphisms
SNPs within 2kb(291 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010294 ADAM-TS Spacer 1
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
InterPro IPR013273 Peptidase M12B, ADAM-TS
InterPro IPR002870 Peptidase M12B, propeptide
InterPro IPR010909 PLAC
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000032169 a disintegrin and metalloproteinase with thrombospondin motifs 10
References
(Earliest) J:80645 Carninci P, et al., High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2147031

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory