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Adamts10
Gene Detail
 Symbol
Name
ID
Adamts10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
MGI:2449112
Synonyms ZnMP
Feature Type protein coding gene
Genetic Map
Chromosome 17
17.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:33524204-33553782 bp, + strand
From VEGA annotation of GRCm38

  29579 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:81940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Adamts10

Human
homologs
Human Homolog ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif, 10
NCBI Gene ID 81794
neXtProt AC  NX_Q9H324
Human Synonyms  ADAM-TS10, ADAMTS-10, WMS, WMS1
Human Chr (Location)  19p13.2; chr19:8580240-8610753 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human ADAMTS10
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(7) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Adamts10 interacts with 322 markers (Mir1b, Mir15a, Mir15b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process proteolysis
Component extracellular matrix, extracellular region, ...
Function hydrolase activity, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (10)   
Theiler Stages: 9, 11, 16, 28
Assay TypeResults
RT-PCR 10
cDNA source data(60)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(63) Genomic(1) cDNA(60) Primer pair(2)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000037200 (Evidence)
Ensembl Gene ModelENSMUSG00000024299 (Evidence)
Entrez Gene224697 (Evidence)
UniGene29304
DFCITC1585303, TC1589888, TC1596488, TC1598563, TC1601729, TC1602010, TC1603545, TC1629663, TC1631953, TC1746559
DoTSDT.101372374, DT.101375322, DT.101375323, DT.101375324, DT.101736805, DT.102550893, DT.490329, DT.55209798, DT.91404765, DT.94181424, DT.94240849, DT.97353014
EC3.4.24.-
Consensus CDS ProjectCCDS37566.1
International Mouse Knockout Project StatusAdamts10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000037200 VEGA Gene Model | MGI Sequence Detail 29579 C57BL/6J ±  kb
transcript OTTMUST00000095898 VEGA | MGI Sequence Detail 4043 Not Applicable 
polypeptide OTTMUSP00000053537 VEGA | MGI Sequence Detail 1104 Not Applicable 

For the selected sequences
All sequences(112) RefSeq(18) UniProt(4)
Polymorphisms SNPs within 2kb(291 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR010294 ADAM-TS Spacer 1
InterPro IPR024079 Metallopeptidase, catalytic domain
InterPro IPR001590 Peptidase M12B, ADAM/reprolysin
InterPro IPR013273 Peptidase M12B, ADAM-TS
InterPro IPR002870 Peptidase M12B, propeptide
InterPro IPR010909 PLAC
InterPro IPR000884 Thrombospondin, type 1 repeat
Protein Ontology PR:000032169 A disintegrin and metalloproteinase with thrombospondin motifs 10
References (Earliest) J:80645 Carninci P, et al., High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)
Other
accession IDs
MGI:2147031

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory