Adamts10
Gene Detail

Symbol Name ID

Adamts10 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10 MGI:2449112

Synonyms

ZnMP

Feature Type

protein coding gene

Genetic Map

Chromosome 17

17.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr17:33524204-33553782 bp, + strand From VEGA annotation of GRCm38   29579 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:81940  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Adamts10

Human homologs

Human Homolog		ADAMTS10, ADAM metallopeptidase with thrombospondin type 1 motif, 10
NCBI Gene ID		81794
neXtProt AC		NX_Q9H324
Human Synonyms		ADAM-TS10, WMS, WMS1
Human Chr (Location)		19p13.2; chr19:8645126-8675588 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human ADAMTS10

Alleles and phenotypes

All alleles(9) : Targeted(2) Gene trapped(7)

Gene Ontology (GO) classifications

All GO classifications: (15 annotations)

Process	proteolysis
Component	extracellular matrix, extracellular region, ...
Function	hydrolase activity, metal ion binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (10)    Tissues (10)   
Theiler Stages: 9, 11, 16, 28

Assay Type	Results
RT-PCR	10

cDNA source data(64)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(67) Genomic(1) cDNA(64) Primer pair(2)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000037200 (Evidence)
Ensembl Gene Model	ENSMUSG00000024299 (Evidence)
Entrez Gene	224697 (Evidence)
UniGene	29304
DFCI	TC1585303, TC1589888, TC1596488, TC1598563, TC1601729, TC1602010, TC1603545, TC1629663, TC1631953, TC1746559
DoTS	DT.101372374, DT.101375322, DT.101375323, DT.101375324, DT.101736805, DT.102550893, DT.490329, DT.55209798, DT.91404765, DT.94181424, DT.94240849, DT.97353014
EC	3.4.24.-
Consensus CDS Project	CCDS37566.1
International Mouse Knockout Project Status	Adamts10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000037200	VEGA Gene Model | MGI Sequence Detail	29579	C57BL/6J
transcript	OTTMUST00000095898	VEGA | MGI Sequence Detail	4043	Not Applicable
polypeptide	OTTMUSP00000053537	VEGA | MGI Sequence Detail	1104	Not Applicable

All sequences(98) RefSeq(4) UniProt(4)

Polymorphisms

SNPs(182 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR010294	ADAM-TS Spacer 1
InterPro	IPR024079	Metallopeptidase, catalytic domain
InterPro	IPR001590	Peptidase M12B, ADAM/reprolysin
InterPro	IPR013273	Peptidase M12B, ADAM-TS
InterPro	IPR002870	Peptidase M12B, propeptide
InterPro	IPR010909	PLAC
InterPro	IPR000884	Thrombospondin, type 1 repeat
Protein Ontology	PR:000032169	A disintegrin and metalloproteinase with thrombospondin motifs 10

References

(Earliest) J:80645 Carninci P, et al., High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(36)

Other accession IDs

MGI:2147031