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Carmil3 Gene Detail
Summary
  • Symbol
    Carmil3
  • Name
    capping protein regulator and myosin 1 linker 3
  • Synonyms
    Lrrc16b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448573
    NCBI Gene: 268747
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55490651-55508272 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448573
protein coding gene Chr14:55490651-55508272 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021344
protein coding gene Chr14:49520000-49537181 (+)
A/J MGP_AJ_G0021303
protein coding gene Chr14:48536409-48553547 (+)
AKR/J MGP_AKRJ_G0021279
protein coding gene Chr14:50283150-50300282 (+)
BALB/cJ MGP_BALBcJ_G0021307
protein coding gene Chr14:48481725-48498869 (+)
C3H/HeJ MGP_C3HHeJ_G0021087
protein coding gene Chr14:49967672-49985147 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021745
protein coding gene Chr14:52010975-52028150 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019292
protein coding gene Chr14:46913205-46930812 (+)
CAST/EiJ MGP_CASTEiJ_G0020606
protein coding gene Chr14:46227698-46244842 (+)
CBA/J MGP_CBAJ_G0021054
protein coding gene Chr14:53569880-53587058 (+)
DBA/2J MGP_DBA2J_G0021175
protein coding gene Chr14:48256550-48273699 (+)
FVB/NJ MGP_FVBNJ_G0021157
protein coding gene Chr14:47712024-47729136 (+)
LP/J MGP_LPJ_G0021249
protein coding gene Chr14:50559719-50576855 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021181
protein coding gene Chr14:52931930-52949118 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021772
protein coding gene Chr14:49466589-49483750 (+)
PWK/PhJ MGP_PWKPhJ_G0020353
protein coding gene Chr14:44791581-44809340 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020181
protein coding gene Chr14:45457323-45474482 (+)
WSB/EiJ MGP_WSBEiJ_G0020659
protein coding gene Chr14:49748072-49765543 (+)



Homology
more
  • Human Ortholog
    CARMIL3, capping protein regulator and myosin 1 linker 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CARMIL3, capping protein regulator and myosin 1 linker 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf121, crml-1, LRRC16B
  • Links
    NCBI Gene ID: 90668
    neXtProt AC: NX_Q8ND23
    UniProt: Q8ND23

  • Chr Location
    chr14:24051997-24069729 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 268747 NCBI Gene Model | MGI Sequence Detail 17622 C57BL/6J ±  kb
transcript NR_155103 RefSeq | MGI Sequence Detail 5087 C57BL/6  
polypeptide Q3UFQ8 UniProt | EBI | MGI Sequence Detail 1375 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:270494 Spence EF, et al., In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019 Jan 23;10(1):386

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory